73015-46-0Relevant academic research and scientific papers
Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: Synthesis, structure-activity relationships, and pharmacokinetics
Ndungu, J. Maina,Krumm, Stefanie A.,Yan, Dan,Arrendale, Richard F.,Reddy, G. Prabhakar,Evers, Taylor,Howard, Randy,Natchus, Michael G.,Saindane, Manohar T.,Liotta, Dennis C.,Plemper, Richard K.,Snyder, James P.,Sun, Aiming
, p. 4220 - 4230 (2012/06/30)
The measles virus (MeV), a member of the paramyxovirus family, is an important cause of pediatric morbidity and mortality worldwide. In an effort to provide therapeutic treatments for improved measles management, we previously identified a small, non-nucl
Therapeutic amides
-
, (2008/06/13)
Amides having formula I: STR1 wherein E, X, R2 and R3 have the meanings given in the specification, and pharmaceutically acceptable salts and pharmaceutically acceptable in vivo hydrolysable esters thereof, which are useful in the treatment of urinary incontinence. Further provided are processes for preparing the amides and pharmaceutical compositions containing them.
