73120-83-9

Usage

Physical State

Colorless liquid

Odor

Faint amine odor

Uses

+ Solvent
+ Gas treating
+ Production of dyes, pharmaceuticals, and personal care products
+ Corrosion inhibitor
+ Chemical intermediate in the synthesis of other compounds

Health Hazards

Can cause skin and eye irritation, prolonged exposure may have harmful effects on human health

Safety Precautions

Handle with care, store and handle in a well-ventilated area away from heat and ignition sources, and flammable.

Upstream product

• 2242-31-1 2-(N-methylaminomethyl)-2,3-dihydro-1,4-benzodioxin 
• 107-07-3 2-chloro-ethanol 
• 540-51-2 2-bromoethanol 
• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 4739-94-0 ethyl 2,3-dihydro-1,4-benzodioxin-2-carboxylate 
• 21398-80-1 N-methyl-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide 

Downstream Products

• 119746-89-3 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-{2-[(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-methyl-amino]-ethyl} ester 5-isopropyl ester 
• 112358-09-5 2-amino>ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 
• 119746-86-0 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-{2-[(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-methyl-amino]-ethyl} ester 5-methyl ester 

Relevant academic research and scientific papers

Design and synthesis of substituted compounds containing the 1,4- benzodioxin subunit. New potential calcium antagonists

New compounds possessing 1,4-benzodioxin or its saturated analogous heterocyclic system were synthesized and tested for calcium antagonist activity. Biological differences were seen between the different modifications applied. These compounds have been shown to be representative of a novel series of calcium channel antagonists. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

New 1,4-dihydropyridine derivatives combining calcium antagonism and α-adrenolytic properties

A series of twelve 1,4-dihydropyridine derivatives incorporating an α-adrenergic moiety in one of the ester chains was synthesized. The compounds were evaluated for their calcium antagonist activities by the inhibition of [3H]nitrendipine bindi