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TLN-4601 is a novel and potent small-molecule inhibitor of the protein phosphatase, CDC25. It has demonstrated promising anti-cancer activity in preclinical studies, making it a potential candidate for further development as a cancer therapy.

733035-26-2

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733035-26-2 Usage

Uses

Used in Oncology:
TLN-4601 is used as an anti-cancer agent for its ability to inhibit the growth of cancer cells and induce cell cycle arrest, leading to a decrease in tumor growth and progression.
Used in Cancer Therapy Development:
TLN-4601 is used as a potential candidate for further development in cancer therapy due to its favorable safety profile and good pharmacokinetics in animal models, offering new treatment options for cancer patients in the future.

Check Digit Verification of cas no

The CAS Registry Mumber 733035-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,3,0,3 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 733035-26:
(8*7)+(7*3)+(6*3)+(5*0)+(4*3)+(3*5)+(2*2)+(1*6)=132
132 % 10 = 2
So 733035-26-2 is a valid CAS Registry Number.

733035-26-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3,10-trihydroxy-5-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]-11H-benzo[b][1,4]benzodiazepin-6-one

1.2 Other means of identification

Product number -
Other names BU-4664L

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:733035-26-2 SDS

733035-26-2Downstream Products

733035-26-2Relevant academic research and scientific papers

METHODS OF SYNTHESIZING FARNESYL DIBENZODIAZEPINONES

-

, (2021/12/08)

The present invention is directed to synthetic means for producing farnesyl dibenzodiazepinone compounds, including AMO-01.

First synthesis of BU-4664L

Takahashi, Yusuke,Hirokawa, Takafumi,Watanabe, Mai,Fujita, Satomi,Ogura, Yusuke,Enomoto, Masaru,Kuwahara, Shigefumi

, p. 5670 - 5672 (2015/09/21)

The first synthesis of BU-4664L, an actinomycte-produced N-farnesylated dibenzodiazepinone with important biological activities, has been achieved in 18% overall yield from a known benzoic acid derivative by a nine-step sequence that involves an intramolecular Buchwald-Hartwig coupling of a sterically demanding bromo amine intermediate to install the unique tricyclic ring system.

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