7334-12-5

Usage

InChI:InChI=1/C24H18N2O/c27-26(24-17-13-22(14-18-24)20-9-5-2-6-10-20)25-23-15-11-21(12-16-23)19-7-3-1-4-8-19/h1-18H/b26-25-

Upstream product

• 92-93-3 1-phenyl-4-nitrobenzene 
• 6810-26-0 4-hydroxylaminobiphenyl 
• 60-29-7 diethyl ether 
• 92-52-4 biphenyl 
• 92-67-1 4-phenylalanine 
• 7647-01-0 hydrogenchloride 
• 119273-47-1 O-Acetyl-N-(4-biphenyl)hydroxylamine 
• 100-61-8 N-methylaniline 

Downstream Products

• 4088-58-8 4,4'-hydrazodibiphenyl 
• 5326-53-4 1,2-di([1,1'-biphenyl]-4-yl)diazene 
• 92-69-3 4-Phenylphenol 
• 92-96-6 N,N'-bis-biphenyl-4-yl-thiourea 
• 92-67-1 4-phenylalanine 

Relevant academic research and scientific papers

Organocatalytic oxidation of substituted anilines to azoxybenzenes and nitro compounds: Mechanistic studies excluding the involvement of a dioxirane intermediate

An organocatalytic and environmentally friendly approach for the selective oxidation of substituted anilines was developed. Utilizing a 2,2,2-trifluoroacetophenone-mediated oxidation process, substituted anilines can be transformed into azoxybenzenes, while a simple treatment with MeCN and H2O2 leads to the corresponding nitro compounds, providing user-friendly protocols that can be easily scaled up. Various substitution patterns and functional groups were tolerated leading to products in high to excellent yields. Mechanistic studies utilizing HRMS provide clear evidence for the distinct mechanistic intermediates that are involved. This study constitutes an indirect proof excluding the involvement of a dioxirane intermediate in the green organocatalytic oxidation, utilizing 2,2,2-trifluoroacetophenone as the catalyst.

Ruthenium nanoparticle-catalyzed, controlled and chemoselective hydrogenation of nitroarenes using ethanol as a hydrogen source

This communication describes a ruthenium nanoparticle-catalyzed reduction of nitroarenes giving azoxyarenes, azoarenes, or anilines in good to excellent yields using ethanol as a hydrogen source. Copyright

S(N)2 at nitrogen: The reaction of N-(4-cyanophenyl)-O-diphenylphosphinoylhydroxylamine with N-methylaniline. A model for the reactions of ultimate carcinogens of aromatic amines with (bio)nucleophiles

The model reaction of 5 with 6 to give 7 and 8 (≥90%) follows the S(N)2 mechanism. From this result and from product studies it is concluded that the reactions of the ultimate carcinogen 1 with 6 and deoxyguanosine (dG) (and hence of other ultimate carcinogens of aromatic amines with bionucleophiles) follow the same mechanism.