73436-03-0Relevant articles and documents
PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS
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Paragraph 00348; 00358, (2021/12/08)
The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected from alumina and aluminum alkoxides and in a non-protic solvent wherein at least one carbon atom ortho to the hydroxy group in the hydroxy aryl compound is unsubstituted. The present application also includes compounds of Formula (I).
CATALYTIC CANNABIGEROL PROCESSES AND PRECURSORS
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, (2021/10/11)
The present disclosure relates to cannabigerol sulfonate esters and processes for their use to prepare cannabigerol (CBG) and related compounds, including cannabigerobutol (CBGB), cannabigerovarin (CBGV), and cannabigerophorbol (CBGP). In a preferred embodiment, the cannabigerol sulfonate ester is (E)-4-(3, 7-5 dimethylocta-2,6-dienyl)-3,5-bis(trimetbylsilyloxy)phenyl trifluoromethanesulfonate. In a preferred process, the trifluoromethansulfonate leaving group is replaced by an alkyl group. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of cannabigerol and related compounds from the cannabigerol sulfonate esters.
Synthesis of bryophyte components 2. Syntheses of prenylated bibenzyl derivatives
Eicher,Tiefensee,Donig,Pick
, p. 98 - 102 (2007/10/02)
Efficient and expeditious syntheses of the biologically active prenylated bibenzyl derivatives 1a-d are developed giving rise to their access on a preparative scale.
Synthesis of Bibenzyl Cannabinoids, Hybrids of Two Biogenetic Series Found in Cannabis sativa
Crombie, Leslie W.,Crombie, W. Mary L.,Firth, David F.
, p. 1263 - 1270 (2007/10/02)
Syntheses of a series of compounds which merge a m-dihydroxybibenzyl with a terpenoid structure, giving a series of hybrid cannabinoids in which products of two major biogenetic routes of Cannabis are united, are described.The compounds made are the biben
AMORPHASTILBOL, AN ANTIMICROBIAL AGENT FROM AMORPHA NANA
Mitscher, Lester A.,Gollapudi, Sitaraghav Rao,Drake, Steven,Oburn, David S.
, p. 1481 - 1484 (2007/10/02)
Key Word Index - Amorpha nana; Leguminosae; amorphastilbol; 3,5-dihydroxy-7,4'-dimethoxyflavone; antimicrobial agents; chemistry; bioactivity.Abstract - Bioassay-directed fractionation of Amorpha nana demonstrated that the anti Gram positive/antitubercular constituent is amorphastilbol.The chemical structure of amorphastilbol was confirmed by chemical transformation to known (Radula variabilis) dihydroamorphastilbol and its methyl ether.Inactive 3,5-dihydroxy-7,4'-dimethoxyflavone was detected in this plant for the first time and identified by interconversion with kaempferol.All compounds were evaluated in vitro for antimicrobial spectrum and potency.