736150-32-6Relevant articles and documents
Synthesis and antibacterial activity of a novel series of DNA gyrase inhibitors: 5-[(E)-2-arylvinyl]pyrazoles
Tanitame, Akihiko,Oyamada, Yoshihiro,Ofuji, Keiko,Terauchi, Hideo,Kawasaki, Motoji,Wachi, Masaaki,Yamagishi, Jun-Ichi
, p. 4299 - 4303 (2005)
The 2-arylvinyl moiety in 1-(3-chlorophenyl)-3-(4-piperidyl)-5-[(E)-2-(5- chloro-1H-indol-3-yl)vinyl]pyrazole 2, which has previously shown improved DNA gyrase inhibition and target-related antibacterial activity, was transformed to other groups and the i