73696-35-2

Usage

Uses

Used in Pharmaceutical Research:
5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a promising candidate for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one is utilized as a versatile building block for the creation of a wide range of organic compounds. Its ability to participate in various chemical reactions allows for the synthesis of complex molecules with diverse properties and potential applications.
Used in Medicinal Chemistry:
5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one plays a significant role in medicinal chemistry, where it is employed as a structural component in the design and development of new drugs. Its unique features contribute to the discovery of compounds with improved pharmacological properties and therapeutic potential.
Used in Drug Discovery:
As a valuable tool in drug discovery efforts, 5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one aids researchers in identifying and optimizing novel compounds with potential biological activity. Its presence in a compound can influence its pharmacokinetic and pharmacodynamic properties, making it an important factor in the development of effective therapeutic agents.

Upstream product

• 52580-57-1 2-benzamide-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester 
• 5936-58-3 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid 
• 108-94-1 cyclohexanone 
• 98-88-4 benzoyl chloride 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 90543-03-6 4,5,6,7-Tetrahydro-2-(triphenylphosphoranylidenamino)benzothiophen-3-carbonsaeure-ethylester 
• 52535-73-6 4,5,6,7-tetrahydrobenzothiophene-2-benzoylamino-3-carboxylic acid 

Downstream Products

• 108561-29-1 4-(diethylamino)-5,6,7,8-tetrahydro-3-methyl-2-phenylbenzo<4,5>thieno<2,3-b>pyridine 
• 356586-88-4 N-[3-(piperidine-1-carbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-yl]benzamide 
• 312948-88-2 C₂₀H₂₂N₂O₃S 
• 35149-36-1 2-phenyl-4-methoxy-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidine 
• 35149-32-7 4-chloro-2-phenyl-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 1321621-02-6 2-phenyl-4-benzyloxy-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidine 
• 73696-42-1 2-benzamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbohydrazide 
• 62349-19-3 2-phenyl-3-amino-5,6,7,8-tetrahydro-4H-benzothieno[2,3-d]pyrimidin-4-one 
• 19819-18-2 2-phenyl-5,6-tetramethylenethieno<2,3-d>pyrimidin-4(3H)-one 
• 25174-48-5 2-phenyl-5,6,7,8-tetrahydro-4H-benzothieno[2,3-d]pyrimidine-4(3H)-thione 
• 296770-68-8 2-benzamido-N-cyclohexyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 
• 328278-79-1 2-benzamido-N-(4-methoxylphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 
• 119934-23-5 2-benzamido-N-(2-hydroxyethyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 
• 455898-84-7 2-benzamido-N-benzyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 

Relevant academic research and scientific papers

Synthesis of some new tetrahydrobenzo[b] thiophene derivatives and tetrahydrobenzo-thienopyrimidine derivatives under microwave irradiation

2-Phenyl-5,6,7,8-tetrahydro-4H-benzothieno[2,3-d][1,3]oxazin-4-one (4) was reacted with either aliphatic or aromatic primary amines such as benzylamine, cyclohexylamine, p-toluidine, and=or p-anisidine to give carboxamide derivatives 5a-d, respectively. A

A new, general approach for the synthesis of heteroannulated 3,1-oxazin-4-ones

β-(N-Triphenylphosphoranyliden)-enamino esters afford the synthetically useful heteroannulated 3,1-oxazin-4-ones with aroyl chlorides in different solvents. The reaction proceeds in one step and in high yields and appears to be independent of the reactivity of the heterocyclic substrate.

Heterocyclic β-Enamino Esters, 27. Synthesis of Heterocondensed 6H-1,3-Oxazin-6-ones from N-Acylenamino Esters in the System Triphenylphosphane/Hexachloroethane/Triethylamine

A simple ring closure reaction of N-acylenamino esters (1b, e, 2, 3a - f, 7) in the system triphenylphosphane/hexachloroethane/triethylamine is described proceeding with high yields.Under chlorinating 3-ester cleavage heterocondensed 6H-1,3-oxazin-6-ones

FUNCTIONAL DERIVATIVES OF THIOPHENE. 18. SYNTHESIS OF 4-OXOTHIENOOXAZINE DERIVATIVES AND THIOPHENE-3-CARBOXYLIC ACID HYDRAZIDES

2-Aryl-4-oxothienooxazine derivatives were synthesized.Opening of the oxazine ring to give 2-benzamidothiophene-3-carboxylic acid hydrazide derivatives is observed when these compounds are treated with hydrazine hydrate.