73875-27-1

Basic information

• Product Name: 2-Methyl-3,4,5,6-tetramethoxybromobenzene
• Synonyms: 2-BROMO-3,4,5,6-TETRAMETHOXYTOLUENE;2-METHYL-3,4,5,6-TETRAMETHOXYBROMOBENZENE;2-bromo-3,4,5-tetramethoxy toluene;1-broMo-2,3,4,5-tetraMethoxy-6-Methylbenzene
• CAS NO: 73875-27-1
• Molecular Formula: C₁₁H₁₅BrO₄
• Molecular Weight: 291.14
• Product Categories: Benzene derivates
• Mol File: 73875-27-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 317°C at 760 mmHg
• Flash Point: 128°C
• Appearance: /
• Density: 1.336g/cm³
• Vapor Pressure: 0.000735mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Methyl-3,4,5,6-tetramethoxybromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-3,4,5,6-tetramethoxybromobenzene(73875-27-1)
• EPA Substance Registry System: 2-Methyl-3,4,5,6-tetramethoxybromobenzene(73875-27-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 73875-27-1(Hazardous Substances Data)

Usage

Chemical Properties

Off-white Cryst

InChI:InChI=1/C11H15BrO4/c1-6-7(12)9(14-3)11(16-5)10(15-4)8(6)13-2/h1-5H3

Upstream product

• 72326-72-8 2-bromo-3,4,5-trimethoxy-1-methylbenzene 
• 6443-69-2 3,4,5-trimethoxytoluene 
• 21450-56-6 1,2,3,4-tetramethoxybenzene 
• 150626-26-9 1,2,4-trimethoxy-6-methylbenzene-3-ol 
• 25245-39-0 1-bromo-2,3,4,5-tetramethoxybenzene 
• 13909-73-4 2',3',4'-trimethoxyacetophenone 
• 36776-51-9 2,3,6-tribromo-4-methyl-phenol 
• 106-44-5 p-cresol 
• 19676-64-3 2,3,4-trimethoxyphenol 
• 65884-12-0 2,3,4,5-tetramethoxybenzaldehyde 
• 3066-90-8 2,3-dimethoxy-5-methylbenzene-1,4-diol 
• 605-94-7 2,3-Dimethoxy-5-methyl-1,4-benzoquinone 

Downstream Products

• 83036-57-1 (E)-1-(3,7-dimethylocta-2,6-dien-1-yl)-2,3,4,5-tetramethoxy-6-methylbenzene 
• 30685-17-7 2-bromo-5,6-dimethoxy-3-methylcyclohexane-2,5-diene-1,4-dione 
• 71573-66-5 1‐allyl‐2,3,4,5‐tetramethoxy‐6‐methylbenzene 
• 94828-31-6 methyl (E)-2-methyl-4-(2,3,4,5-tetramethoxy-6-methylphenyl)but-2-en-1-ol 
• 764723-80-0 1-(3-hydroxypropyl)-2,3,4,5-tetramethoxy-6-methylbenzene 
• 918800-77-8 2,3,4,5-tetramethoxy-6-methylphenylmagnesium bromide 
• 35896-58-3 2,3,4,5-tetramethoxytoluene 
• 849034-07-7 3-bromo-2,6-dimethyl-8-(2-methyl-3,4,5,6-tetramethoxyphenyl)oct-6-en-2-ol 
• 99348-11-5 4-methyl-6-(2-methyl-3,4,5,6-tetramethoxyphenyl)hex-4-enoic acid 
• 85216-20-2 4-methyl-6-(2-methyl-3,4,5,6-tetramethoxyphenyl)hex-4-en-1-ol 
• 85228-79-1 1-<(2E)-6,7-epoxy-3,7-dimethyloct-2-enyl>-2,3,4,5-tetramethoxy-6-methylbenzene 
• 26539-07-1 4-methyl-6-(3-methyl-5,6-dimethoxy-1,4-benzoquinon-2-yl)hex-4-enoic acid 

Relevant articles and documents

Efficient synthesis of 5-bromo-2,3-dimethoxy-6-methyl-1,4-benzoquinone: key intermediate for preparing Coenzyme Q

The title compound, a key intermediate for preparing Coenzyme Qn family, was prepared in an excellent yield by a reaction sequence starting from the commercially available 3,4,5-trimethoxytoluene 1 via bromination, methoxylation and oxidation reactions. A

2,3-Dimethoxy-5-methyl-1,4-benzoquinones and 2-methyl-1,4-naphthoquinones: Glycation inhibitors with lipid peroxidation activity

Anti-glycation activity of our anti-oxidant quinone library was measured and several 2,3-dimethoxy-5-methyl-1,4-benzoquinones and 2-methyl-1,4- naphthoquinones were identified as novel inhibitors of glycation, of which 2,3-dimethoxy-5-methyl-1,4-benzoquinones 13b is the most potent glycation inhibitor with around 50 μM of the IC50 value.

SYNTHESIS OF UBIQUINONE AND MENAQUINONE ANALOGUES BY OXIDATIVE DEMETHYLATION OF ALKENYLHYDROQUINONE ETHERS WITH ARGENTIC OXIDE OR CERIC AMMONIUM NITRATE IN THE PRESENCE OF 2,4,6-PYRIDINE-TRICARBOXYLIC ACID

It was found that alkenylhydroquinone ethers demethylated with argentic oxide or ceric ammonium nitrate in the presence of 2,4,6-pyridinetricarboxylic acid as a catalyst and afforded ubiquinone-2, menaquinone-2 and their analogs in yields of 53 to 89 percent.The new approach to the synthesis of starting alkenylhydroquinone ethers as well as 2,4,6-pyridinetricarboxylic acid and its derivatives has been reported.