73882-47-0

Basic information

• Product Name: 1H-Pyrazole, 3-methyl-5-phenyl-1-(phenylmethyl)-
• CAS NO: 73882-47-0
• Molecular Formula: C17H16N2
• Molecular Weight: 248.327
• Mol File: 73882-47-0.mol

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole, 3-methyl-5-phenyl-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole, 3-methyl-5-phenyl-1-(phenylmethyl)-(73882-47-0)
• EPA Substance Registry System: 1H-Pyrazole, 3-methyl-5-phenyl-1-(phenylmethyl)-(73882-47-0)

Safety Data

• Hazardous Substances Data: 73882-47-0(Hazardous Substances Data)

Upstream product

• 20570-96-1 benzylhydrazine dihydrochloride 
• 93-91-4 1-phenylbutan-1,3-dione 
• 23652-90-6 (2Z)-3-amino-1-phenylbut-2-en-1-one 
• 32064-65-6 benzylhydrazine oxalate 
• 70769-77-6 (Z)-4-Ethylsulfanyl-4-phenyl-but-3-en-2-one 
• 555-96-4 Benzylhydrazine 
• 95514-24-2 (Z)-1-amino-1-phenyl-1-buten-3-one 
• 56426-41-6 3-methyl-5-phenylpyrazole 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Relevant articles and documents

Regioselective synthesis of multisubstituted pyrazoles via cyclocondensation of β-thioalkyl-α,β-unsaturated ketones with hydrazines

Multisubstituted pyrazoles were efficiently synthesized by cyclocondensation of β-thioalkyl-α,β-unsaturated ketones with hydrazines under relatively mild conditions. A one-pot synthetic protocol through tandem Liebeskind-Srogl cross-coupling/cyclocondensation using a-oxo ketene dithioacetals as the starting materials was also realized for the same purpose.

Scope and limitations in the regioselective synthesis of 1,3,5-trisubstituted pyrazoles from β-amino enones and hydrazine derivatives. 13C-chemical shift prediction rules for 1,3,5-trisubstituted pyrazoles

β-amino enones react with hydrazine derivatives to give regioselectively 1,3,5-trisubstituted pyrazoles. The synthetic method only presents limitations when the β-substituent of the enone and the hydrazine substituent are bulky or possess an electron withdrawing character. Comparison of the 13C-NMR spectra of the seventy pyrazoles allowed us to estimate a 13C-chemical shift prediction rule for 1,3,5-trisubstituted pyrazoles, with deviations of less than ± 1 ppm.

Porphyrins with four azole substituents in meso positions: X-ray crystal structure of meso-tetrakis-(1-benzylpyrazol-4-yl)-porphyrin at 200 K

Several new porphyrins have been prepared in improved yields using an established method which was adapted to formylpyrazoles bearing on the pyrazole N1-nitrogen protective groups. The deprotection of N-para-methoxybenzyl and SEM protected meso

Orientation de la reaction d'alkylation des pyrazoles dans des conditions neutres et en catalyse par transfert de phase

The N-butylation and N-benzylation of nine pyrazoles bearing different substituents in positions 3 and 5 have been studied in neutral and basic medium (phase transfer catalysis).The orientation of the reaction depends strongly on the method used when the