73908-04-0Relevant articles and documents
Direct halogenation of alcohols with halosilanes under catalyst- and organic solvent-free reaction conditions
Ajvazi, Njomza,Stavber, Stojan
supporting information, p. 2430 - 2433 (2016/05/19)
A chemoselective method for the direct halogenation of different types of alcohols with halosilanes under catalyst- and solvent-free reaction conditions (SFRC) is reported. Various primary, secondary and tertiary benzyl alcohols and tertiary alkyl alcohols were directly transformed to the corresponding benzyl and alkyl halides, respectively, using chlorotrimethylsilane (TMSCl) and bromotrimethylsilane (TMSBr).
Conversion of alcohols to bromides using a fluorous phosphine
Desmaris, Laurence,Percina, Nathalie,Cottier, Louis,Sinou, Denis
, p. 7589 - 7591 (2007/10/03)
Reaction of alcohols with the fluorous phosphine-carbon tetrabromide complex in toluene or in a two-phase toluene-FC-72 system afforded the corresponding bromides in good yields. The fluorous-phosphine oxide is readily separated by liquid-liquid extraction, providing an alternative to the homogeneous triphenylphosphine-carbon tetrachloride conversion, as well as to the polymer-supported phosphine method. The fluorous phosphine oxide could be reduced and the product reused.
DECOMPOSITION DES ESTERS DE LA N-HYDROXYTHIOPYRIDONE-2. SYNTHESE DE QUELQUES NOUVEAUX HALOGENURES SECONDAIRES ET TERTIAIRES ENCOMBRES.
Stofer, Edmond,Lion, Claude
, p. 623 - 628 (2007/10/02)
Hindered α,α-disubstituted and α,α,α-trisubstituted acyl chlorides give with N-hydroxy-2-thiopyridone, the corresponding esters.The decomposition of this compound in tetrachloromethane or in bromotrichloromethane as solvent and halogen atom source results in the formation of new very hindered secondary R1R2CHX (R1 = iPr or tBu; R2 = iPr or tBu; X = Cl or Br) and tertiary R1R2R3CX (R1 = R2 = R3 = iPr; R1 = tBu, R2 = iPr, R3 = Et or Me, X = Cl) alkyl halides.