7422-66-4

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 10497-05-9 Tris(trimethylsilyl) phosphate 
• 107-46-0 Hexamethyldisiloxane 
• 95-50-1 1,2-dichloro-benzene 

Downstream Products

• 34234-03-2 7-cyclohex-1-enyl-azepan-2-one 
• 52334-07-3 2-phenyloxazolo<5,4-b>pyridine 
• 107757-10-8 6-Acetylamino-8-methyl-1-tetralone 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 

Relevant academic research and scientific papers

Benzoxa condensed ring compounds, process for producing the same and pharmaceutical composition comprising the same

Pharmaceutical compositions containing a benzoxazole compound and a 2,3-dihydrobenzofuran compound represented by the following formula (I) and its pharmaceutically acceptable salt: STR1 In the formula, any one of P, Q, R and S is a group represented by t

Para ordered aromatic diacids containing benzimidazole groups

2-Benzimidazole terephthalic acid, 4,4'-dicarboxy-2,2'-bisbenzimidazole benyl and 4,4"-dicarboxy-2'-phenyl-3'-[2-(4-phenylbenzthiazole)]-6'-[2-(3-phenylbenzimidazole]-p-terphenyl are provided. Also provided are methods for preparing these dicarboxylic acids. 2-benzimidazole terephthalic acid is prepared by reacting trimellitic anhydride with o-phenylenediamine in a suitable solvent. 4,4'-dicarboxy-2,2'-bisbenzimidazole biphenyl is prepared by diazotizing 2-amino-5-bromobenzoic acid to prepare 4,4'-dibromodiphenic acid, reacting the 4,4'-dibromodiphenic acid with o-phenylenediamine in trimethylsilyl polyphosphate solution to prepare 4,4'-dibromo-2,2'-bisbenzimidazolyl biphenyl, reacting the 4,4'-dibromo-2,2'-bisbenzimidazolyl biphenyl with cuprous cyanide to prepare the corresponding dicyano compound, and hydrolyzing the dicyano compound. 4,4"-Dicarboxy-2'-phenyl-3'-[2-(4-phenylbenzthiazole)]-6'-[2-(3-phenylbenzimidazole)]-p-terphenyl is prepared by reacting a 4-benzazole benzil with 1,3-bis(p-bromophenyl)-2-propanone to prepare 2,5-bis(p-bromophenyl)-3-phenyl-4-(2-phenylbenzazole) cyclopentadienone, reacting the cyclopentadienone with 2-(3-ethynylphenyl) benzimidazole to prepare the corresponding dibromo terphenyl compound, reacting the dibromo terphenyl compound with cuprous cyanide to prepare the corresponding dicyano terphenyl compound, and hydrolyzing the dicyano compound.

Benzoxazole derivatives

Novel benzoxazole derivative of the formula: STR1 wherein R is a substituted or unsubstituted phenyl group, a substituted or unsubstituted naphthyl group, a substituted or unsubstituted cycloalkyl group or a substituted or unsubstituted heterocyclic group; Alk is single bond, a substituted or unsubstituted lower alkylene group, a lower alkenylene group or a lower alkynylene group; the group STR2 is a group of the formula: --CH2 -- or --CH=, and a pharmaceutically aceptable salt thereof are disclosed. Said derivative (I) and a salt thereof are useful as therapeutic agents for diabetes.