74411-14-6

Basic information

• Product Name: methyl 2-(3-chlorophenoxy)acetate
• Synonyms: methyl 2-(3-chlorophenoxy)acetate
• CAS NO: 74411-14-6
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 200.61896
• Mol File: 74411-14-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 2-(3-chlorophenoxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(3-chlorophenoxy)acetate(74411-14-6)
• EPA Substance Registry System: methyl 2-(3-chlorophenoxy)acetate(74411-14-6)

Safety Data

• Hazardous Substances Data: 74411-14-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 588-32-9 3-chlorophenoxyacetic acid 
• 108-43-0 3-monochlorophenol 
• 96-34-4 methyl chloroacetate 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 40665-94-9 dimethyl 3-(3-chlorophenoxy)-2-oxopropylphosphonate 
• 35370-95-7 2-(3-chlorophenoxy) ethanethioamide 
• 122623-81-8 methyl 2-(3-chlorophenoxy)propionate 
• 588-32-9 3-chlorophenoxyacetic acid 
• 114476-84-5 2-(3-chlorophenoxy)acetyl chloride 
• 129367-86-8 11-{(1S,2S)-2-[(E)-4-(3-Chloro-phenoxy)-3-oxo-but-1-enyl]-5-oxo-cyclopentyl}-undecanoic acid methyl ester 
• 122437-71-2 7-{(1S,2S)-2-[(E)-4-(3-Chloro-phenoxy)-3-oxo-but-1-enyl]-5-oxo-cyclopentyl}-heptanoic acid methyl ester 
• 129368-04-3 {(1S,2S)-2-[(E)-4-(3-Chloro-phenoxy)-3-oxo-but-1-enyl]-5-oxo-cyclopentyl}-acetic acid methyl ester 
• 129368-00-9 2β-<3-hydroxy-4-(m-chlorophenoxy)-trans-1-butenyl>-5α-hydroxycyclopentyl-1α-acetic acid γ-lactone 

Relevant articles and documents

Design and Synthesis of Novel 4-Hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one Derivatives for Use as Herbicides and Evaluation of Their Mode of Action

In order to develop a novel herbicide containing the β-triketone motif, a series of 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one derivatives were designed and synthesized. The bioassay results showed that compound II15 had good pre-emergent herbicidal activity even at a dosage of 187.5 g ha-1. Moreover, compound II15 showed a broader spectrum of weed control when compared with a commercial herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), and displayed good crop safety to Triticum aestivum L. and Zea mays Linn. when applied at 375 g ha-1 under pre-emergence conditions, which indicated its great potential as a herbicide. More importantly, studying the molecular mode of action of compound II15 revealed that the novel triketone structure is a proherbicide of its corresponding phenoxyacetic acid auxin herbicide, which has a herbicidal mechanism similar to that of 2,4-D. The present work indicates that the 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one motif may be a potential lead structure for further development of novel auxin-type herbicides.

Synthesis of (±) travoprost and its analogs

A new synthetic approach for the antiglaucoma agent, travoprost (1) has been developed in four steps from key intermediate (2). Key transformations include Horner-Wadsworth-Emmons reaction and separation of diastereomers to obtain (±) travoprost (1) and its analogs.

PROSTANOIDS. XIX. THE SYNTHESIS OF 14C-LABELED CLOPROSTENOL

A 1:3400 mixture of 2-14C-labelled methyl bromoacetate with the nonradioactive ester gave labelled dimethoxy-2-oxo-3-(m-chlorophenoxy)phosphonate which was used for the synthesis of 16-14C-labelled cloprostenol by the Corey strategy.