7459-63-4

Usage

Uses

Used in Chemical Analysis:
6-Phenyl-1,3,5-triazine-2,4-diol is used as a reagent in organic synthesis for its ability to form stable complexes with certain organic compounds, which is particularly beneficial in the field of chemical analysis. This property aids in the detection and analysis of various compounds, enhancing the precision and reliability of analytical results.
Used in High-Performance Liquid Chromatography (HPLC):
In the application industry of analytical chemistry, 6-Phenyl-1,3,5-triazine-2,4-diol serves as a crucial component in high-performance liquid chromatography. Its complex-forming ability with organic compounds contributes to the separation and identification processes, thereby improving the efficiency and accuracy of HPLC analyses.
Used in Pharmaceutical Development:
6-Phenyl-1,3,5-triazine-2,4-diol holds potential in the pharmaceutical industry due to its unique chemical properties. It may be utilized in the development of new drugs, where its complex-forming characteristics could be harnessed to improve drug delivery, targeting, or stability.
Used in Materials Science:
In the realm of materials science, 6-Phenyl-1,3,5-triazine-2,4-diol is explored for its potential applications. Its chemical properties might be employed to create new materials with specific characteristics, such as improved stability, reactivity, or other desirable traits for various industrial uses.

InChI:InChI=1/C9H7N3O2/c13-8-10-7(11-9(14)12-8)6-4-2-1-3-5-6/h1-5H,(H2,10,11,12,13,14)

Upstream product

• 1700-02-3 2,4-dichloro-6-phenyl-1,3,5-triazine 
• 6291-91-4 N-(carbamoylcarbamoyl)benzamide 
• 100-47-0 benzonitrile 
• 127099-85-8 N-Cyanoguanidine 
• 46187-84-2 N-(tert-butyl)benzimidamide 
• 99911-94-1 diphenyl iminodicarboxylate 
• 32622-40-5 6-phenyl-4-thioxo-3,4-dihydro-1,3,5-triazin-2(1H)-one 
• 34277-78-6 N-(carbamoylcarbamothioyl)benzamide 
• 102-09-0 bis(phenyl) carbonate 
• 1000668-98-3 phenyl (1-tert-butylamino-1-phenylmethylidene)carbamate 
• 93-58-3 benzoic acid methyl ester 
• 108-19-0 BIURET 

Downstream Products

• 88113-76-2 4-methoxy-1-methyl-6-phenyl-1H-[1,3,5]triazin-2-one 
• 62220-98-8 1,3-dimethyl-6-phenyl-1H-[1,3,5]triazine-2,4-dione 
• 1700-02-3 2,4-dichloro-6-phenyl-1,3,5-triazine 
• 62221-01-6 3,5-di(2-propenyl)-6-phenyl-1,3,5-triazine-2,4-dione 
• 64398-66-9 bis-aziridin-1-yl-phenyl-[1,3,5]triazine 
• 30886-13-6 6-phenyl-1H-[1,3,5]triazine-2,4-dithione 

Relevant academic research and scientific papers

Synthesis method of 2, 4-dihalogen-6-aryl substituted triazine derivative

The invention belongs to the technical field of compound synthesis, and particularly discloses a synthesis method of a 2, 4-dihalogen-6-aryl substituted triazine derivative. The synthesis method comprises the following steps: generating an intermediate triazine diketone compound from an aryl formate compound and biuret under the action of alkali, and reacting under the action of a halogenating reagent to obtain the 2, 4-dihalogen-6-aryl substituted triazine derivative. The method has the characteristics of cheap and accessible raw materials, can greatly lower the production cost, has the advantages of mild reaction conditions, single reaction product, fewer byproducts and no impurity removal difficulty, is simple in technological operation, can easily obtain the high-purity product, and issuitable for large-scale industrial production.

Retro-ene reactions in heterocyclic synthesis. V. A novel synthetic method for 1,3,5-triazine-2,4(1H,3H)-diones

(Chemical Equation Presented) N-t-Butylamidines 1 on heating with diphenyl carbonate (2) at 150-180° gave the 1,3,5-triazine-2,4(1H,3H)-dione derivatives 5. Acylation of amidines 1 and cyclocondensation of the resulting carbamates 3 gave [1,3,5,7]tetrazocine-2,6-dione derivatives 4, and subsequent retro-ene reaction and ring contraction afforded triazine derivatives 5.

Synthesis and antivirus activity of 1,3,5-triazine derivatives

Reaction of 6-phenyl-4-thioxo-1,3,5-triazine-2-one with alkyl halide in the presence of 1 equiv. of sodium hydroxide resulted in 4-alkylthio-6-phenyl-1,3,5-triazine-2-one in good yield, whereas the above reaction provided 2-alkoxyl-4-alkylthio-6-phenyl-1,3,5-triazine in the presence of 2 equiv. of sodium hydroxide. 6-Phenyl-4-thioxo-1,3,5-triazine-2-one was oxidized with hydrogen peroxide to give 6-phenyl-1,3,5-triazine-2,4-dione. Further treatment with ethyl bromoacetate or (substituted) benzyl bromides yielded 2,4-dialkoxy-6-phenyl-1,3,5-triazines. At the same time, a small amount of 2-dimethylamino-4-alkoxy-6-phenyl-1,3,5-triazine were isolated. Preliminary bioassays indicate that the title compounds possess good activities against tobacco mosaic virus.

Retro-ene reactions in heterocyclic synthesis. IV [1]. A new synthetic method for 6-hydroxypyrimidin-4(3H)-ones and 1,3,5-triazine-2,4(1H,3H)- diones

N-t-Butylbenzamidines 1 reacted with diphenyl phenylmalonate or diphenyl methylmalonate to give 6-hydroxypyrimidin-4(3H)-ones 4 or 5. Amidines 1 on reaction with diphenyl imidodicarboxylate afforded 1,3,5-triazine-2,4(1H,3H)- diones 8.