7464-89-3

Usage

Role in Biology

Crucial chemical compound in the synthesis of DNA, RNA, and proteins in living organisms

Function as Coenzyme

Involved in many biological pathways, including the transfer of one-carbon units in the synthesis of purines, thymidylate, and amino acids

Cellular Metabolism

Regulates cellular metabolism

Cell Growth and Division

Plays a vital role in cell growth and division

Prevention of Neural Tube Defects

Key factor in the prevention of neural tube defects in developing fetuses

Treatment of Anemia

Important in the treatment of certain types of anemia

Cardiovascular Function

Contributes to the maintenance of healthy cardiovascular function

Upstream product

• 5440-00-6 4,5-Diamino-1,3-dimethyluracil 
• 6271-51-8 2,3-dibromo-1-(4-bromo-phenyl)-3-phenyl-propan-1-one 
• 10388-32-6 1-phenyl-3-(4-bromophenyl)-2,3-dibromo-1-propanone 
• 10325-67-4 2,3-dibromo-3-(4-methoxy-phenyl)-1-phenyl-propan-1-one 
• 38895-96-4 p-nitrochalcone dibromide 
• 54987-90-5 2-Nitrochalkondibromid 
• 611-91-6 2,3-dibromo-1,3-diphenylpropane-1-one 
• 7145-87-1 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one 
• 32045-79-7 1-(biphenyl-4-yl)-2,3-dibromo-3-phenylpropan-1-one 
• 38895-95-3 p-chlorochalcone dibromide 

Relevant academic research and scientific papers

5,5′-bipyridyl-2,4,6,2′,4′,6′-hexaone derivatives (hydurilic acids): Syntheses, mechanism of C-C-Bond formation and properties of the dimeric barbituric acid derivatives

A series of hydurilic acid derivatives (5,5′-bipyrimidinyl-2,4,6,2′,4′,6′-hexaones) including several new derivatives was synthesized from 5,6-diaminouracils. Mechanisms for their formation are proposed and discussed. Furthermore, a new method for the preparation of pyrimidine-2,4,5,6-tetraone-5-oxime derivatives (violuric acids) was found starting from 5-amino-6-nitrosouracils.

REACTIONS OF 5,6-DIAMINO-1,3-DIMETYLURACIL WITH HALOGEN DERIVATIVES OF CHALCONES

The reaction of 5,6-diamino-1,3-dimethyluracil with 1,3-diaryl-2,3-dibromopropan-1-ones gave β-(5-amino-6-imino-1,3-dimethyluracil)chalcones, and conditions for their cyclocondensation to pyrimidinodiazepines were found.For substantiation of the reaction mechanism, the reaction of the diamine with other halogen derivatives of chalcones was studied.The IR, UV, and mass spectra of the synthesized compounds and their condensation products are discussed.