1,2-Bis(p-tolylimino)ethylene dichloride

Base Information

• Chemical Name: 1,2-Bis(p-tolylimino)ethylene dichloride
• CAS No.: 7472-70-0
• Molecular Formula: C16H14Cl2N2
• Molecular Weight: 305.207
• NSC Number: 401962
• DSSTox Substance ID: DTXSID70322746
• Nikkaji Number: J911.856J
• Mol file: 7472-70-0.mol

Synonyms:7472-70-0;NSC401962;SCHEMBL10066905;DTXSID70322746;NSC-401962;1,2-Bis(p-tolylimino)ethylene dichloride;(1Z,2Z)-N~1~,N~2~-Bis(4-methylphenyl)ethanebis(imidoyl) dichloride

Chemical Property of 1,2-Bis(p-tolylimino)ethylene dichloride

Chemical Property:

• XLogP3: 6.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 304.0534038
• Heavy Atom Count: 20
• Complexity: 327

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)N=C(C(=NC2=CC=C(C=C2)C)Cl)Cl

Technology Process of 1,2-Bis(p-tolylimino)ethylene dichloride

There total 5 articles about 1,2-Bis(p-tolylimino)ethylene dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N,N'-Di-p-tolyloxalamide (3299-61-4) → N,N'-bis(4-methylphenyl)ethanediimidoyl dichloride (7472-70-0)

Guidance literature:

With phosphorus pentachloride; In toluene; Heating;

DOI:10.1002/prac.19953370130

Reference yield:

oxalyl dichloride (79-37-8) + p-toluidine (106-49-0,12221-03-3) → N,N'-bis(4-methylphenyl)ethanediimidoyl dichloride (7472-70-0)

Guidance literature:

oxalyl dichloride; p-toluidine; In toluene; at 20 ℃; for 0.5h;

With phosphorus pentachloride; In toluene; at 100 ℃;

DOI:10.1055/s-0029-1217071

Reference yield:

Oxalamide (471-46-5) + toluene (108-88-3,15644-74-3,16713-13-6) → N,N'-bis(4-methylphenyl)ethanediimidoyl dichloride (7472-70-0)

Guidance literature:

With phosphorus pentachloride; Reflux;

upstream raw materials:

N,N'-Di-p-tolyloxalamide

phosphorus pentachloride

toluene

p-Toluidinium-oxalat

Downstream raw materials:

5-methyl-indole-2,3-dione

4,4'-(di-p-tolyl-oxalodiimidoyl)-bis-morpholine

N,N'-Bis--1,2-bis-<4-tolylimino>-ethan-1,2-diamin

N,N'-Bis-<(S)-1-Phenethyl>-1,2-bis-<4-tolylimino>-ethan-1,2-diamin