749905-01-9

Upstream product

• 108-24-7 acetic anhydride 
• 62023-62-5 allophenylnorstatine 
• 167678-46-8 3-acetoxy-2-methylbenzoyl chloride 
• 478411-22-2 (2S,3S)-3-(3-Acetoxy-2-methyl-benzoylamino)-2-hydroxy-4-phenyl-butyric acid 

Downstream Products

• 1026299-75-1 (2S,3S)-2-acetoxy-3-(3-acetoxy-2-methyl-benzoylamino)-4-phenyl-butyric acid chloride 
• 478410-84-3 KNI-1317 
• 853411-65-1 acetic acid 3-{(1S,2S)-2-acetoxy-3-[(4R)-4-allylcarbamoyl-5,5-dimethyl-thiazolidin-3-yl]-1-benzyl-3-oxo-propylcarbamoyl}-2-methyl-phenyl ester 
• 1346870-94-7 C₃₁H₃₄F₅N₃O₇ 

Relevant academic research and scientific papers

Therapeutic combinations

The present invention relates to methods for improving the pharmacokinetics of certain compounds useful as inhibitors of the HIV protease enzyme by inhibiting the enzyme activity of cytochrome P450. The present invention also relates to compositions compr

COMPOSITIONS COMPRISING AN HIV PROTEASE INHIBITOR

The present invention relates to pharmaceutical compositions comprising amorphous (4R)-N-allyl-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, or a pharmaceutically acceptable salt o

Therapeutic combinations

The present invention relates to methods for treating an HIV infection a mammal by administering to the mammal a therapeutically effective amount of a combination of compounds. The present invention also relates to compositions comprising certain compound

Methods of preparing compounds useful as protease inhibitors

The invention relates to methods of preparing compounds of formula (I), useful as inhibitors of the HIV protease enzyme. The present invention also relates to intermediate compounds useful in the preparation of compounds of formula (I).

METHODS OF PREPARING COMPOUNDS USEFUL AS PROTEASE INHIBITORS

The invention relates to methods of preparing compounds of formula (I) that are useful as inhibitors of the HIV protease enzyme. The present invention also relates to intermediate compounds useful in the preparation of compounds of formula (I).