75-82-1

Basic information

• Product Name: 1,2-DIBROMO-1,1-DIFLUOROETHANE
• Synonyms: 1,2-dibromo-1,1-difluoro-ethan;CF2BrCH2Br;Difluorodibromoethane;ethane,1,2-dibromo-1,1-difluoro-;Genetron 132b-B2;genetron132b-b2;HBFC-132B;1,2-DIBROMO-1,1-DIFLUOROETHANE
• CAS NO: 75-82-1
• Molecular Formula: C₂H₂Br₂F₂
• Molecular Weight: 223.84
• EINECS: 200-905-2
• Product Categories: refrigerants
• Mol File: 75-82-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: -61 °C
• Boiling Point: 92-93 °C
• Flash Point: 9.5 °C
• Appearance: /
• Density: 2.224 g/mL at 25 °C(lit.)
• Vapor Pressure: 59.5mmHg at 25°C
• Refractive Index: 1.445-1.447
• CAS DataBase Reference: 1,2-DIBROMO-1,1-DIFLUOROETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIBROMO-1,1-DIFLUOROETHANE(75-82-1)
• EPA Substance Registry System: 1,2-DIBROMO-1,1-DIFLUOROETHANE(75-82-1)

Safety Data

• Hazard Codes: N-Xi,Xi,N
• Statements: 59-36/37/38
• Safety Statements: 37/39-26-59
• RTECS: KH9360000
• Hazardous Substances Data: 75-82-1(Hazardous Substances Data)

Usage

Chemical Properties

clear light yellow liquid

InChI:InChI=1/C2H2Br2F2/c3-1-2(4,5)6/h1H2

Upstream product

• 359-10-4 1-Chloro-2,2-difluoroethene 
• 75-38-7 Vinylidene fluoride 
• 7726-95-6 bromine 
• 591-50-4 iodobenzene 
• 359-08-0 2-bromo-1,1-difluoroethene 
• 630-16-0 1,1,1,2-tetrabromo-ethane 
• 420-46-2 2,2,2-trifluoroethanol 

Downstream Products

• 75-38-7 Vinylidene fluoride 
• 359-08-0 2-bromo-1,1-difluoroethene 
• 598-73-2 1-bromo-1,2,2-trifluoroethene 
• 3832-48-2 bromodifluoroacetyl chloride 
• 156020-87-0 2,2-difluoro-1-phenylcyclopropanecarbaldehyde 
• 108-86-1 bromobenzene 
• 92-52-4 biphenyl 

Relevant articles and documents

Method for preparing ethyl difluorobromoacetate

The invention discloses a method for preparing ethyl difluorobromoacetate, which comprises the following steps: by taking CF2Cl-CH2Cl as a raw material, firstly removing HCl to obtain CF2 = CHCl, then carrying out addition on the CF2 = CHCl and bromine to obtain CF2Br-CHClBr, then reacting the CF2Br-CHClBr with oxygen and a photoinitiator under the photocatalysis to obtain CF2Br-COCl, and finally carrying out esterification reaction on the CF2Br-COCl and ethanol to obtain the ethyl difluorobromoacetate. According to the method, a photooxidation reaction process is adopted in the CF2Br-COCl preparation process, the conversion rate of CF2Br-CHClBr and the selectivity of CF2Br-COCl are very high, meanwhile, the use of strong-corrosivity concentrated sulfuric acid or a sulfur trioxide oxidizing agent or a mercury-containing high-toxicity catalyst is avoided, and the process is green and environmentally friendly.

A New Route for the Preparation of Substituted 2,2-Difluorostyrenes and a Convenient Route to Substituted (2,2,2-Trifluoroethyl)benzenes

The (2,2-difluoroethenyl)zinc reagent II is coupled with aryl iodides or bromides in the presence of Pd(PPh3)4 in DMF to give the corresponding 2,2-difluorostyrenes IV. The 4-substituted (tetrafluoroaryl)copper reagents are coupled with 2,2-difluoro-1-iodoethylene (I) to produce the corresponding styrene derivatives VII. Both methods provide good yields of the coupled products. These products react with wet KF in DMF or DMSO to form the (2,2,2-trifluoroethyl)benzene derivatives VIII in good yields.