7505-73-9

Usage

Uses

Used in Organic Synthesis:
1-(2-phenylquinolin-4-yl)ethanone is used as a synthetic intermediate for the development of various organic compounds. Its unique structure allows it to be a valuable building block in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(2-phenylquinolin-4-yl)ethanone is used as a potential candidate for drug discovery. Its quinoline ring system and phenyl group may contribute to its interaction with biological targets, making it a promising compound for the development of new pharmaceuticals.
Used in Material Science:
1-(2-phenylquinolin-4-yl)ethanone may also find applications in material science, where its specific chemical and physical properties could be utilized in the creation of novel materials with unique characteristics for various industrial applications.

Upstream product

• 7664-93-9 sulfuric acid 
• 894789-64-1 N-methoxy-N-methyl-2-phenylquinoline-4-carboxamide 
• 676-58-4 methylmagnesium chloride 
• 612-96-4 2-Phenylquinoline 
• 111-34-2 -butyl vinyl ether 
• 122-51-0 orthoformic acid triethyl ester 
• 59661-86-8 2-phenylquinoline-4-carbonyl chloride 
• 132-60-5 cinchophen 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 4979-79-7 4-chloro-2-phenylquinoline 
• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 
• 81564-30-9 4-methoxycarbonylacetyl-2-phenylquinoline 1-oxide 
• 65417-19-8 methyl 2-phenylquinoline-4-carboxylate 1-oxide 
• 1423-60-5 methyl ethynyl ketone 

Downstream Products

• 5442-77-3 4-[(2-phenyl-[4]quinolyl)-thioacetyl]-morpholine 
• 101575-93-3 2-bromo-1-(2-phenyl-4-quinolinyl)ethanone 
• 930802-16-7 2-phenyl-4-(1H-pyrazol-3-yl)quinoline 

Relevant academic research and scientific papers

Metal-, Photocatalyst-, and Light-Free Minisci C-H Acetylation of N-Heteroarenes with Vinyl Ethers

Herein, we report a mild, operationally simple method for Minisci C-H acetylation of N-heteroarenes using vinyl ethers as robust, inexpensive acetyl sources. The reactions do not require a conventional photocatalysis, electrocatalysis, metal catalysis, light activation, or high temperature. This method is thus significantly more sustainable than previously reported methods in terms of cost, reagent toxicity, and waste generation. This protocol can be expected to obtain medically relevant molecules from abundant feedstock materials.

Iron-Catalyzed Minisci Type Acetylation of N-Heteroarenes Mediated by CH(OEt)3/TBHP

Iron-catalyzed acetylation of electron deficient N-heteroarenes has been reported using triethylorthoformate as robust and inexpensive acetyl source. This new method is successfully applied for the acetylation of quinolines, isoquinoline, quinoxalines, arylpyridines, bipyridines, and benzothiazole.

QUINOLINES DERIVATIVES AS NOVEL ANTICANCER AGENTS

The invention provides quinoline derivatives, their manufacture, pharmaceutical compositions containing them, and their use as medicaments. The active compounds of the present invention are useful for the treatment of proliferative neoplastic and nonneoplastic diseases.

Imidazole and imidazoline derivatives and uses thereof

This invention is directed to novel imidazole and imidazoline derivatives which are selective agonists for cloned human α2 adrenergic receptors. This invention is also related to the use of these compounds for the treatment of any disease where

Aromatic Annelation by Reaction of Arylimidoyl Radicals with Alkynes: a New Synthesis of Quinolines

An easily effected aromatic annelation is described, involving the reaction of arylimidoyl radicals with alkynes to give quinolines.

Studies on the N-Oxides of ?-Deficient N-Heteroaromatics. XXXVI. Photochemical and Thermal Michael Reactions of Alcohols with Methyl 2-Phenyl-3,1-benzoxazepine-5-carboxylate and Its Derivatives

Irradiation (>/=300 nm) of methyl 2-phenyl-3,1-benzoxazepine-5-carboxylate in an alcohol afforded the Z-isomer of methyl 3-alkoxy-2-(2-benzamidophenyl)-acrylate as the major product.In contrast, thermal reaction of the oxazepine with a primary alcohol in