75075-28-4Relevant academic research and scientific papers
Pd-catalyzed cross-coupling reactions of amides and aryl mesylates
Dooleweerdt, Karin,Fors, Brett P.,Buchwald, Stephen L.
supporting information; experimental part, p. 2350 - 2353 (2010/07/06)
A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.
Proteomimetic compounds and methods
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, (2008/06/13)
The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
AN UNUSUAL SYNTHESIS OF NICOTINAMIDES
Harrington, Philip M.
, p. 683 - 687 (2007/10/02)
Reaction of 2,3-pyridinedicarboxylic anhydride (1) with a substituted aniline (2) in acetic acid gave rise to a mixture of two products.These two products were identified as the cyclic imide (4) and nicotinamide (5).A mechanistic scheme consistent with empirical observations is proposed.
Tetrahydronicotinamide derivative, pharmaceutical compositions and use
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, (2008/06/13)
1,4,5,6-Tetrahydronicotinamide derivative represented by the formula: STR1 (wherein R is defined in the specification), a process of preparing the same and pharmaceutical composition containing the same are disclosed. The compound has action for suppressi
