75156-08-0

Upstream product

• 16838-89-4 2,3,5-tri-O-benzyl-D-ribofuranose 
• 10160-87-9 Propiolaldehyde diethyl acetal 
• 69309-71-3 3,3-diethoxyprop-1-ynylmagnesium bromide 

Downstream Products

• 65101-21-5 tri-O-benzyl-aldehydo-D-allo-4,7-anhydro-2,3-dideoxy-oct-2-ynose 
• 59967-95-2 3(5)-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyrazole 
• 75156-00-2 1-(2,4-dinitrophenyl)-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazole 
• 71052-62-5 (2S,3R,4S,5R)-2-[1-(2,4-Dinitro-phenyl)-1H-pyrazol-3-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol 
• 75155-99-6 1-(2,4-dinitrophenyl)-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyrazole 
• 75173-95-4 1-(2,4-dinitrophenyl)-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-4-nitropyrazole 
• 75155-98-5 1,1-diethoxy-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)prop-2-yne 
• 76116-33-1 1,1-diethoxy-3-(2,3,5-tri-O-benzyl-α-D-ribofuranosyl)prop-2-yne 

Relevant academic research and scientific papers

A New Synthesis of Formycin via Nitropyrazole Derivatives

3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the 1-nitro group in the 1,4-dinitro-pyrazole (10).

C-Nucleoside Studies. Part 10. A New Synthesis of 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)pyrazole and its Conversion into 4-Nitro-3(5)-β-D-ribofuranosylpyrazole

1,1-Diethoxy-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)prop-2-yne (12) has been synthesised from 2,3,5-tri-O-benzyl-D-ribofuranose in 52percent yield.Acidic hydrolysis followed by reaction with hydrazine affords 3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyraz