75178-16-4

Basic information

• Product Name: 2-(4-Acetamidophenyl)ethyl acetate
• Synonyms: 2-(4-Acetamidophenyl)ethyl acetate
• CAS NO: 75178-16-4
• Molecular Weight: 221.256
• Mol File: 75178-16-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(4-Acetamidophenyl)ethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Acetamidophenyl)ethyl acetate(75178-16-4)
• EPA Substance Registry System: 2-(4-Acetamidophenyl)ethyl acetate(75178-16-4)

Safety Data

• Hazardous Substances Data: 75178-16-4(Hazardous Substances Data)

Upstream product

• 127-09-3 sodium acetate 
• 108-24-7 acetic anhydride 
• 104-10-9 2-(4'-aminophenyl)ethyl alcohol 
• 75178-12-0 2,2'-bipyridyl-6-yl acetate 
• 155164-63-9 2-acetyl-4,5-dichloropyridazin-3(2H)-one 
• 83345-11-3 N-[4-(2-hydroxylethyl)phenyl]acetamide 
• 75-36-5 acetyl chloride 

Downstream Products

• 92959-73-4 4-acetamido-3-nitrophenethyl acetate 
• 83345-11-3 N-[4-(2-hydroxylethyl)phenyl]acetamide 
• 15896-61-4 2-(4-amino-3-nitrophenyl)ethanol 
• 169883-33-4 2-(4-amino-3-bromophenyl)ethan-1-ol 
• 1374606-80-0 4-acetamido-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylethyl acetate 

Relevant articles and documents

Facile esterification of alcohols with 2-Acyl-4,5-dichloropyridazin-3(2 H)-ones under Friedel-Crafts conditions

This paper describes the esterification of aromatic and aliphatic alcohols by using 2-acyl-4,5-dichloropyridazin-3(2H)-ones as an acyl source under Friedel-Crafts conditions. Twelve alcohols were reacted with four 2-acyl-4,5-dichloropyridazin-3(2H)-ones in the presence of AlCl3 in tetrahydrofuran at room temperature to give the corresponding esters in moderate to excellent yields. Thus, 2-acylpyridazin-3(2H)-ones serve as good and atom-economic acyl sources for the esterification of aromatic alcohols under Friedel-Crafts conditions, representing a rapid, practical, and efficient method of esterification. Georg Thieme Verlag Stuttgart. New York.

Catalyst-free esterification of alcohols using 2-acyl-4,5- dichloropyridazinones under microwave conditions

Efficient and green esterification is of great importance. In this work, we demonstrate the catalyst-free esterification of alcohols by their reaction with 2-acyl-4,5-dichloropyridazin-3(2H)-ones under microwave irradiation. Aliphatic and aromatic alcohols were converted into the corresponding esters in good to excellent yields under microwave irradiation in solvent or solvent-free conditions. It is noteworthy that the reaction is catalyst-free, atom-economic, and rapid and that the process is inexpensive.

Therapeutic substituted indole compounds and compositions thereof

The present invention is concerned with compounds of formula (I) STR1 wherein R, R1 and R2 are independently selected from hydrogen and C1-4 alkyl; R3 and R4 are independently selected from hydrogen, C1-6 alkyl (including cycloalkyl) and aryl (wherein the alkyl or aryl group, which latter includes benzyl, is optionally substituted by one or more atoms or groups independently selected from halogen, C1-4 alkyl and aryl), provided R3 benzyl or substituted benzyl when R4 =H; m is an integer of from 0 to 2; n is an integer of from 0 to 3; (W) is a group of formula (i), (ii), (iii), or (iv) STR2 wherein Y is selected from oxygen, methylene and >N--R5, where R5 is hydrogen, C1-4 alkyl, or benzyl, Z and Z' are independently selected from >C=O, >C=S and methylene, and the chiral center * in formula (i) or (ii) is in its (S) or (R) form or is a mixture thereof in any proportions; X is a group selected from aryl (including heteroaryl) xanthenyl dibenzofuranyl which group is optionally substituted; and salts and solvates thereof, the preparation of these compounds, pharmaceutical formulations containing them and their use in medicine, particularly in the treatment of migraine.