753020-01-8

Upstream product

• 91326-83-9 (4S,5S)-dimethyl 2-phenyl-1,3-dioxolane-4,5-dicarboxylate 
• 25636-49-1 3,3-dimethoxypentane 
• 84379-52-2 (2R,3R)-3-(benzyloxy)butane-1,2,4-triol 

Downstream Products

• 850223-33-5 (R)-4-((E)-(R)-1-Benzyloxy-hexadec-2-enyl)-2,2-diethyl-[1,3]dioxolane 
• 753020-10-9 (3S,4S,5S)-3-N,N-dibenzylamino-4,5-dibenzyloxy-6-octadecyn-(1E)-enephosphonic acid 
• 753020-09-6 dimethyl (3S,4S,5S)-3-N,N-dibenzylamino-4,5-dibenzyloxy-6-octadecyn-(1E)-enephosphonate 
• 753020-08-5 (2S,3S,4S)-2-N,N-dibenzylamino-3,4-dibenzyloxy-5-octadecyn-1,3,4-triol 
• 1053626-17-7 (2R,3S,4S)-3,4-Bis-benzyloxy-2-dibenzylamino-octadec-5-ynal 
• 1054820-39-1 (R)-4-((1R,2S)-1,2-Bis-benzyloxy-hexadec-3-ynyl)-2,2-diethyl-[1,3]dioxolane 
• 753020-07-4 (2S,3S,4S)-2-azido-3,4-dibenzyloxy-5-octadecyn-1,3,4-triol 
• 1053714-00-3 (2S,3S,4S)-2-Amino-3,4-bis-benzyloxy-octadec-5-yn-1-ol 
• 753020-06-3 (2R,3R,4S)-3,4-dibenzyloxy-5-octadecyn-1,2,3,4-tetrol 
• 753020-11-0 (2R,3R,4S)-3-O-benzyl-1,2-O-(3'-pentylidene)-5-octadecyn-1,2,3,4-tetrol 
• 753020-04-1 (2R,3R)-3-O-benzyl-1,2-O-(3'-pentylidene)-4-oxo-5-octadecyn-1,2,3-triol 
• 753020-03-0 (2R,3R)-3-O-benzyl-1,2-O-(3'-pentylidene)-5-octadecyn-1,2,3,4-tetrol 
• 753020-02-9 (2R,3S)-2-O-benzyl-3,4-O-(3'-pentylidene)-2,3,4-trihydroxybutanal 

Relevant academic research and scientific papers

Synthesis of L-lyxo-phytosphingosine and its 1-phosphonate analogue using a threitol acetal synthon

The first synthesis of an isosteric phosphonate analogue of the aminotriol lipid phytosphingosine (3), together with an improved synthesis of (2S,3S,4S)-phytosphingosine (2), are described. A key intermediate is 3-pentylidene acetal 9, which was prepared in two steps from dimethyl 2,3-0-benzylidene-D-tartrate (7).

Enantioselective construction of 6-substituted-α,β-unsaturated- δ-lactone: Total synthesis of anti-bacterial agent (-)-cleistenolide

An efficient and straightforward stereoselective synthesis of α,β-unsaturated lactone (1) cleistenolide is described. The synthesis was started from commercially available d-tartaric acid and completed within 13 steps with an overall yield of 7.92%. The cis-olefin was generated from Still-Gennari protocol and one of the hydroxyl groups was from dihydroxylation methodology. All the reactions were very clean and the products were obtained in very good yields.