753020-03-0Relevant articles and documents
Synthesis of L-lyxo-phytosphingosine and its 1-phosphonate analogue using a threitol acetal synthon
Lu, Xuequan,Byun, Hoe-Sup,Bittman, Robert
, p. 5433 - 5438 (2007/10/03)
The first synthesis of an isosteric phosphonate analogue of the aminotriol lipid phytosphingosine (3), together with an improved synthesis of (2S,3S,4S)-phytosphingosine (2), are described. A key intermediate is 3-pentylidene acetal 9, which was prepared in two steps from dimethyl 2,3-0-benzylidene-D-tartrate (7).