7538-44-5

Basic information

• Product Name: BIS(2-HYDROXYETHYL)-3-AMINOPROPYLTRIETHOXYSILANE
• Synonyms: BIS(2-HYDROXYETHYL)-3-AMINOPROPYLTRIETHOXYSILANE;BIS(2-HYDROXYETHYL)AMINOPROPYLTRIETHOXYSILANE;3-[BIS(2-HYDROXYETHYL)AMINO]PROPYL-TRIETHOXYSILANE;N-(3-TRIETHOXYSILYLPROPYL)DIETHANOLAMINE;2,2’-[[3-(triethoxysilyl)propyl]imino]bis-ethano;2,2'-[[3-(triethoxysilyl)propyl]imino]bisethanol;3-(BIS(2-HYDROXYETHYL)AMINO)PROPYL-TRIET HOXYSILANE SOL.;bis(2-hydroxyethyl)-3-aminopropyltriethoxysilane62%inethanol
• CAS NO: 7538-44-5
• Molecular Formula: C₁₃H₃₁NO₅Si
• Molecular Weight: 309.47
• EINECS: 231-408-9
• Mol File: 7538-44-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 380.2 °C at 760 mmHg
• Flash Point: 24°C
• Appearance: /
• Density: 0.92
• Refractive Index: 1.4090
• PKA: 14.40±0.10(Predicted)
• CAS DataBase Reference: BIS(2-HYDROXYETHYL)-3-AMINOPROPYLTRIETHOXYSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(2-HYDROXYETHYL)-3-AMINOPROPYLTRIETHOXYSILANE(7538-44-5)
• EPA Substance Registry System: BIS(2-HYDROXYETHYL)-3-AMINOPROPYLTRIETHOXYSILANE(7538-44-5)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26
• RIDADR: UN 1170 3/PG 3
• WGK Germany: 1
• TSCA: Yes
• Hazardous Substances Data: 7538-44-5(Hazardous Substances Data)

Usage

Uses

3-[Bis(2-hydroxyethyl)amino]propyl-triethoxysilane solution was used to functionalize nanoporous silica (SBA-15).

Synthetic route

(3-chloropropyl)triethoxysilane (5089-70-3) + 2,2'-iminobis[ethanol] (111-42-2) → 3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5)

Conditions	Yield
With potassium iodide In dimethyl sulfoxide at 120℃; Inert atmosphere;

3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5) + ethanol (64-17-5) + trimethylaluminum (75-24-1) → C15H34AlNO6Si

Conditions	Yield
In toluene at 0℃; for 4h; Inert atmosphere; Schlenk technique;	95%

3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5) + ethanol (64-17-5) + dibutylmagnesium (1191-47-5) → C14H33MgNO6Si

Conditions	Yield
In n-heptan1ol at 0 - 20℃; for 4h; Inert atmosphere; Schlenk technique;	91%

3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5) + ethanol (64-17-5) + aluminum isopropoxide (555-31-7) → C15H34AlNO6Si

Conditions	Yield
In toluene at 0℃; for 4h; Inert atmosphere; Schlenk technique;	88%

titanium(IV) isopropylate (546-68-9) + 3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5) → C19H43NO7SiTi

Conditions	Yield
In ethanol; dichloromethane at 20℃; for 4h; Inert atmosphere; Schlenk technique;

3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5) → C23H43N5O9Si

Conditions	Yield
Multi-step reaction with 2 steps 1.1: 35 h / 80 °C / Inert atmosphere 1.2: 0.75 h / 150 °C / Inert atmosphere 2.1: water / 2 h / 85 °C View Scheme

3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5) → C35H65N5O9Si2

Conditions	Yield
Multi-step reaction with 3 steps 1.1: 35 h / 80 °C / Inert atmosphere 1.2: 0.75 h / 150 °C / Inert atmosphere 2.1: water / 2 h / 85 °C 3.1: ethanol / 3 h / 40 °C View Scheme

1,6-dicyanatohexane + 3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane (7538-44-5) → C29H55N5O9Si

Conditions	Yield
Stage #1: 1,6-dicyanatohexane; 3-[bis(2-hydroxyethyl)amino]propyltriethoxysilane at 80℃; for 35h; Inert atmosphere; Stage #2: With tin(IV) chloride at 150℃; for 0.75h; Inert atmosphere;

Upstream product

• 5089-70-3 (3-chloropropyl)triethoxysilane 
• 111-42-2 2,2'-iminobis[ethanol] 

Relevant articles and documents

Preparation method of organic silicon toughened isocyanate resin based on chemical bonding (by machine translation)

Under the catalysis of potassium iodide, hydroxyl is introduced, hydroxyl is introduced, hydroxyl is introduced, hydroxyl is introduced into an ethanol solution of 3 - dodecyl triethoxysilane, hydroxyl is introduced, hydroxyl is introduced, and finally silanol cyanate is immersed in a dodecyl trimethyl diisocyanate ethanol solution to obtain the modified hexamethylene diisocyanate. M1, and finally, the silicon alcohol M1 cyanate ester is immersed in an aqueous solution to obtain the modified hexamethylene diisocyanate resin, and finally, the hydroxyl is introduced into an ethanol solution of M3 the dodecyl trimethyl diisocyanate to obtain the modified hexamethylenediisocyanate resin. (by machine translation)