75534-18-8

Upstream product

• 130089-19-9 1-bromo-2-(2-methoxyethenyl)benzene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 96557-30-1 2-bromophenylacetaldehyde 
• 1074-16-4 2-bromophenylethyl alcohol 
• 103-82-2 phenylacetic acid 

Downstream Products

• 319493-66-8 5-[2-(2-chloroethyl)phenyl]dihydrofuran-2-one 
• 30516-40-6 3-phenyl-2,3-dihydro-1H-inden-1-ol 
• 1961-97-3 3-phenyl-1H-indene 
• 1033629-58-1 sodium 2-(2-bromo-phenyl)ethanesulfonate 
• 1238588-10-7 C₈H₁₀BClO₂ 
• 1379674-62-0 1-(2-chloroethyl)-2-ethynylbenzene 
• 1379674-99-3 C₁₃H₁₇ClSi 
• 2039-88-5 2-bromostyrene 
• 406954-89-0 1-[2-(2-bromophenyl)ethyl]-4-(cyclohexylcarbonyl)-1,3,4-trihydropyrazin-2-one 
• 31236-96-1 1-phenyl-2,3-dihydrobenzo[b]phosphole-1-oxide 
• 108954-95-6 1-phenyl-2,3-dihydro-1H-arsindole 

Relevant academic research and scientific papers

Synthesis and characterization of 1-methyl-1-silaindane and 1-methyl-1-germaindane

New synthetic routes to 1-methyl-1-silaindane (1b) and 1-methyl-1-germaindane (1b) were developed and the desired products were obtained in good isolated yield. Compounds 1a and 1b were fully characterized by mass spectroscopy, 1H and 13/

Gold-catalyzed oxidative cyclizations of cis-3-En-1-ynes to form cyclopentenone derivatives

Golden tendencies: The title reaction for synthesizing cyclopentenone derivatives utilizes a gold complex and 8-methylquinoline oxide as the catalyst system (see scheme; IPr=1,3-bis(diisopropylphenyl)imidazol-2-ylidene). Such products are not attainable using diazocarbonyl reagents, as the gold carbenoids tend to react with C-H bonds. Copyright

One-pot synthesis of aminoenone via direct reaction of the chloroalkyl enone with NaN3: Rapid access to polycyclic alkaloids

(Figure presented) A new one-pot procedure for the preparation of aminoenone from chloroalkyl enone and sodium azide was demonstrated. The structure of the presumed triazoline intermediate in this process was confirmed by X-ray analysis for the first time. As the application of this methodology, the synthesis of polycyclic alkaloid hexahydroapoerysopine (1a) was achieved through an efficient synthetic route.

CYCLIC SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE

The present invention is directed to cyclic sulfonamide derivatives of formula (I): or a pharmaceutically acceptable salt thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevent

Lithiophenylalkyllithiums: New dilithium reagents having both sp2- and sp3-hybridised remote carbanionic centres

The reaction of chloro-(2-chloroethyl)benzenes (1), 4-chloro-(3-chloropropyl)benzene (3) or 4-chlorophenyl chloromethyl ether (5) with lithium power using naphthalene as the electron shuttle (8 mol%) in the presence of different carbonyl compounds [Busub

A new synthesis of 3-substituted-1H-indenes through reaction of o-(β-magnesioalkyl)phenylmagnesium dihalides with carboxylate esters

A new synthesis of 3-substituted-1H-indenes has been developed through the reaction of o-(β-magnesioalkyl)phenylmagnesium dihalides with carboxylate esters, followed by dehydration of the intermediate 1-substituted-1-indanols. Di-Grignard reagents allowing the synthesis of 3-substituted-, 2-methyl-3-substituted-, and 4-methyl-3-substituted-1H-indenes have been prepared, with overall yields for the two-step sequence ranging from 45 to 95%.

Six-membered-ring annulation via a conjugate addition/alkylation sequence using functionalized aryllithium reagents and vinyl sulfones

A new method, which is a one-flask procedure involving addition of substituted aryllithium reagents 6 to vinyl sulfones 8 and 9 followed by spontaneous intramolecular alkylation of the resulting α-lithio sulfones, has been developed for the annulation of tetrahydronaphtalene moieties onto preexisting carbon frameworks.The aryllithium reagents employed in this study are the previously investigated intermediates obtained by the chemoselective lithium-halogen exchange reactions of simple as well as oxygenated o-halo-β-phenethyl halides 5.The annulation products 11 and 12 may be subjected to various further transformations which should makethe overall sequences of considerable utility in the synthesis of steroids and other polycyclic systems.