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N1,N3-Bis[4-(trifluoromethyl)phenyl]malonamide is a chemical compound with the molecular formula C16H10F6N2O2. It is a white crystalline solid that belongs to the class of malonamide derivatives. N1,N3-BIS[4-(TRIFLUOROMETHYL)PHENYL]MALONAMIDE is characterized by the presence of two 4-(trifluoromethyl)phenyl groups attached to the N1 and N3 positions of the malonamide backbone. The trifluoromethyl group (-CF3) is a common functional group in pharmaceuticals and agrochemicals, known for its electron-withdrawing and lipophilic properties. The compound may have potential applications in the synthesis of various organic compounds or as an intermediate in the preparation of pharmaceuticals, given its unique structure and properties. However, specific applications and toxicity data are not provided here, and further research would be required to understand its full potential and safety profile.

7574-50-7

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7574-50-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7574-50-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,7 and 4 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7574-50:
(6*7)+(5*5)+(4*7)+(3*4)+(2*5)+(1*0)=117
117 % 10 = 7
So 7574-50-7 is a valid CAS Registry Number.

7574-50-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N'-bis[4-(trifluoromethyl)phenyl]propanediamide

1.2 Other means of identification

Product number -
Other names HMS574B17

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7574-50-7 SDS

7574-50-7Relevant academic research and scientific papers

SUBSTITUTED 2-ARYLMETHYLENE-N-ARYL-N'-ARYL-MALONAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS

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Page/Page column 47, (2008/06/13)

The present invention is directed to substituted 2-arylmethylene-N-aryl-N'-aryl-malonamides and analogs thereof. The present invention also relates to the discovery that the compounds are activators of caspases and inducers of apoptosis. Therefore, the activators os caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of anormal cells occurs.

A new rational hypothesis for the pharmacophore of the active metabolite of leflunomide, a potent immunosuppressive drug

Bertolini, Giorgio,Aquino, Mario,Biffi, Mauro,D'Atri, Gaetano,Di Pierro, Francesco,Ferrario, Francesco,Mascagni, Paolo,Somenzi, Flavio,Zaliani, Andrea,Leoni, Flavio

, p. 2011 - 2016 (2007/10/03)

Leflunomide is one of the most promising disease-modifying antirheumatic drug now in clinical trials for the treatment of rheumatoid arthritis. Metabolic studies have indicated that leflunomide is rapidly processed in vivo to an active metabolite, A771726

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