758-42-9 Usage
General Description
1,1,1-Trichlorotrifluoroacetone, also known as trifluoroacetyl chloride, is a colorless, volatile liquid with a pungent odor. It is a highly reactive chemical compound that is primarily used as a reagent in organic synthesis and as a solvent in chemical reactions. 1,1,1-Trichlorotrifluoroacetone is also used as a starting material in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and potential for harmful health effects, including irritation to the eyes, skin, and respiratory system, as well as central nervous system depression, it is important to handle this chemical with caution and ensure proper safety measures are in place when working with it. Additionally, it is considered environmentally hazardous and should be handled and disposed of properly to prevent harm to the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 758-42-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,5 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 758-42:
(5*7)+(4*5)+(3*8)+(2*4)+(1*2)=89
89 % 10 = 9
So 758-42-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F5O/c1-2(14)3-4(9)6(11)8(13)7(12)5(3)10/h2,14H,1H3
758-42-9Relevant articles and documents
Reductive alkylation of perfluorocarboxylic acid esters with CCl 3F or CCl4 and synthesis of higher linear perfluoroketones
Zeifman, Yu.V.,Postovoi
, p. 1815 - 1819 (2007/10/03)
Barbier-type reductive alkylation of perfluorocarboxylic acid esters (I) with CFCl3 and activated Al was successfully performed to give α,α-dichloroperfluoroketones (II). A similar reaction of CF 3COOEt with CCl4 and Al provided a convenient synthesis of CF3COCCl3. Ketones (II) were fluorinated further with SbF5 to form higher linear perfluoroketones (IX). An alternative approach to the synthesis of ketones (IX) was proposed by reductive perfluoroalkylation of esters (I) under the action of RFI and Al.
Trifluoroacetylation of amino acids and peptides under neutral conditions.
Panetta,Casanova
, p. 4275 - 4277 (2007/10/04)
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