759-97-7

Basic information

• Product Name: 2-BROMO-1 1 3 -TRIMETHOXYPROPANE 95
• Synonyms: 2-BROMO-1 1 3 -TRIMETHOXYPROPANE 95;1-bromo-2-methoxypropionaldimethylacetal;2-bromo-1,1,3-trimethoxy-propan;2-bromo-3-methoxy-propionaldehyddimethylacetal;2-bromo-3-methoxypropionaldehydedimethylacetal;nsc6388;Propane, 2-bromo-1,1,3-trimethoxy-;Propionaldehyde, 2-bromo-3-methoxy-, dimethyl acetal
• CAS NO: 759-97-7
• Molecular Formula: C₆H₁₃BrO₃
• Molecular Weight: 213.06962
• EINECS: 212-074-3
• Product Categories: B;Stains and Dyes;Stains&Dyes, A to
• Mol File: 759-97-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 54-55 °C/21 mmHg(lit.)
• Flash Point: 76 °C
• Appearance: /
• Density: 1.395 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.241mmHg at 25°C
• Refractive Index: n20/D 1.458(lit.)
• CAS DataBase Reference: 2-BROMO-1 1 3 -TRIMETHOXYPROPANE 95(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1 1 3 -TRIMETHOXYPROPANE 95(759-97-7)
• EPA Substance Registry System: 2-BROMO-1 1 3 -TRIMETHOXYPROPANE 95(759-97-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26-36
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 2
• RTECS: TX4185000
• Hazardous Substances Data: 759-97-7(Hazardous Substances Data)

Usage

General Description

2-BROMO-1,1,3-TRIMETHOXYPROPANE 95 is a chemical compound that is primarily used as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. It is a colorless liquid with a strong, sweet odor, and is highly flammable. 2-BROMO-1 1 3 -TRIMETHOXYPROPANE 95 is commonly used as a solvent and reagent in organic synthesis, and is also used as a reactant in the preparation of various compounds. It is important to handle this chemical with caution, as it can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Additionally, it should be stored in a cool, well-ventilated area, away from heat and open flames.

InChI:InChI=1/C6H13BrO3/c1-8-4-5(7)6(9-2)10-3/h5-6H,4H2,1-3H3

Upstream product

• 699012-45-8 2-bromo-3-chloro-1,1-dimethoxy-propane 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 
• 107-02-8 acrolein 
• 5221-17-0 2,3-dibromopropanal 

Downstream Products

• 17576-35-1 1,3,3-trimethoxyprop-1-ene 
• 17576-35-1 1,3,3-trimethoxypropene 
• 16766-15-7 2-(2-Methoxy-4-methyl-phenoxy)-3-methoxy-propanal-dimethylacetal 

Relevant articles and documents

Claisen Orthoester Rearrangement in the Direct Preparation of Z-Isositsirikine and Z-Geissoschizine Derivatives Possessing the Right Oxidation State at C-17

The Claisen orthoester rearrangement utilizing allylic alcohol 1 (or 2) and trimethyl 3-methoxyorthopropionate 13a leads to Z-isositsirikine derivatives 21a-22a (or 23a-24a) possessing one RO-function at C-17.In the cases of trialkyl 3,3-dialkoxyorthopropionates , the intermediate ketene acetals 25a,b do not rearrange according to the Claisen mechanism to form compounds 26a,b and/or possessing two two RO-functions at C-17.Syntheses of the intermediate orthoesters, trimethyl 3-methoxyorthopropionate 13a, trimethyl 3,3-dimethoxyorthopropionate 14a, trimethyl trans-3-methoxyorthoacrylate 20c, and triethyl 3,3-diethoxyorthopropionate 14b are described.