7599-99-7Relevant articles and documents
A tetragonal-looking but twinned orthorhombic structure
Bolte, Michael,Scholtyssik, Maria
, p. 1869 - 1871 (1997)
2,2′-Methylenebis(3-hydroxy-5,5-dimethylcyclohex-2-en-1-one), C17H24O4, forms crystals which appear tetragonal, but are actually orthorhombic. They are twinned on (110). The asymmetric unit consists of two very similar mol
2,2′-Methylenebis(3-hydroxy-5,5-dimethylcyclohex-2-en-1-one)
Low, John N.,Cobo, Justo,Cruz, Silvia,Quiroga, Jairo,Glidewell, Christopher
, p. o666-o668 (2003)
The structure of 2,2′-Methylenebis(3-hydroxy-5,5-dimethylcyclohex-2-en-1-one) was discussed. The compound crystallizes with two independent molecules, both lying across twofold rotation axes in space group Pccn, in a unit cell with dimensions similar to t
Selective synthesis of spiro and dispiro compounds using Mn(III)-based oxidation of tetracarbonyl compounds
Hisano, Kazuki,Nishikawa, Satomi,Nishino, Hiroshi,Shibuya, Keisuke,Yokote, Suzuka
supporting information, (2020/04/21)
The Mn(III)-based oxidation of methylenebis(cyclohexanedione)s and methylenebis(piperidinedione)s as a tetracarbonyl compound was investigated under various conditions, selectively producing spiro dihydrofurans and dispiro cyclopropanes depending on the solvent. The mechanism for the formation of the spiro dihydrofurans and dispiro cyclopropanes was discussed. In addition, a simple synthesis of a new type of alkaloid, 3,4,6,7,8,10-hexahydro-1H-pyrano[3,2-c:5,6-c’]dipyridine-1,9(2H)-diones, was demonstrated.
Methanol as hydrogen source: Transfer hydrogenation of aromatic aldehydes with a rhodacycle
Aboo, Ahmed H.,Bennett, Elliot L.,Deeprose, Mark,Robertson, Craig M.,Iggo, Jonathan A.,Xiao, Jianliang
supporting information, p. 11805 - 11808 (2018/11/10)
A cyclometalated rhodium complex has been shown to perform highly selective and efficient reduction of aldehydes, deriving the hydrogen from methanol. With methanol as both the solvent and hydrogen donor under mild conditions and an open atmosphere, a wide range of aromatic aldehydes were reduced to the corresponding alcohols, without affecting other functional groups.
Evaluation of sodium acetate trihydrate-urea des as a benign reaction media for the Biginelli reaction. Unexpected synthesis of methylenebis(3-hydroxy-5,5-dimethylcyclohex-2-enones), hexahydroxanthene-1,8-diones and hexahydroacridine-1,8-diones
Navarro, Camilo A.,Sierra, Cesar A.,Ochoa-Puentes, Cristian
, p. 65355 - 65365 (2016/07/26)
In this work, the low melting mixture sodium acetate trihydrate-urea was synthesized and the eutectic composition was determined and characterized using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The physical properties
Zinc chloride catalyzed collective synthesis of arylmethylene bis(3-hydroxy-2-cyclohexene-1-ones) and 1,8-dioxo-octahydroxanthene/acridine derivatives
Ganesan, Subramaniapillai Selva,Kothandapani, Jagatheeswaran,Ganesan, Asaithampi
supporting information, p. 682 - 687 (2015/04/14)
Catalytic amount of ZnCl2 efficiently promoted rapid synthesis of arylmethylene bis(3-hydroxy-2-cyclohexene-1-one) in water at room temperature in excellent yield. At elevated temperature, ZnCl2 also catalyzed one-pot synthesis of 1,8-dioxo-octahydroxanthene and 1,8-dioxo-decahydroacridine derivatives in good yield. In specific instances, unusual dissociation of dimedone from the arylmethylene bis(3-hydroxy-2-cyclohexene-1-one) was identified in the reaction medium. It was minimized/avoided by the addition of known excess dimedone to the reaction mixture in the one-pot synthesis of 1,8-dioxo-octahydroxanthene.
Conformational analysis of 2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2- cyclohexene-1-one) by NMR and molecular modeling
De S. Ferreira, Marcelle,Figueroa-Villar, Jose? D.
, p. 935 - 946 (2014/06/24)
2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-ones) with para and ortho-R groups on the benzene ring were prepared and studied by nuclear magnetic resonance (NMR) and molecular modeling to determine their conformational exchanges. Experime
Reaction of aldehydes and 5,5-dimethyl-1,3-cyclohexanedione in the presence of surfactants in water
Qin, Xin-Ying,Jin, Tong-Shou,Zhang, Jian-She,Li, Tong-Shuang
experimental part, p. 1173 - 1178 (2012/03/11)
An efficient and convenient approach to the synthesis of the two different products from aldehydes and 5,5-dimethyl-1,3-cyclohexanedione using two kinds of surfactant catalysts sodium dodecyl sulfate (SDS) and dodecanesulfonic acid (DSA) (10 mol %) is des
Multicomponent reactions of 1,3-cyclohexanediones and formaldehyde in glycerol: Stabilization of paraformaldehyde in glycerol resulted from using dimedone as substrate
Minghao, Li,Chang, Chen,Fei, He,Yanlong, Gua
scheme or table, p. 519 - 530 (2010/06/13)
Glycerol has proved to be an effective promoting medium for many multicomponent reactions of 1,3-cyclohexanediones and formaldehyde. Styrenes, amines, 2-naphthol, 4-hydroxy-6-methyl-2-pyrone and 4-hydroxy-1-methyl-2- quinolone could easily react with 1,3-cyclohexanediones and paraformaldehyde in glycerol under catalyst-free conditions to afford a variety of complex skeletons in fair to excellent yields. In these reactions, glycerol not only showed a significant promoting effect on the reaction yields but also endowed the reaction system with many typical properties of green chemistry, such as cheap, renewable, recyclable and biodegradable solvent, good safety and easy separation of product. The promoting effect of glycerol for the three-component reaction of styrene, dimedone and paraformaldehyde could be attributed to a restricted formation of the methylene intermediate in glycerol. During the reaction, a physical shell, which is mainly composed of a by-product generated in the beginning of the reaction, might be formed in the surface of paraformaldehyde and plays a key role in controlling the formation of the intermediate by means of restricting the decomposition of paraformaldehyde.
Three-component synthesis of hexahydropyridopyrimidine- spirocyclohexanetriones induced by microwave
Quiroga, Jairo,Cruz, Silvia,Insuasty, Braulio,Abonía, Rodrigo,Nogueras, Manuel,Cobo, Justo
, p. 27 - 30 (2007/10/03)
Pyridopyrimidine-spirocyclohexanetriones (5, 6) and pyrimido[4,5-b] quinolinones (8) were obtained in a three-component microwave-assisted reaction of 6-aminopyrimidin-4-ones (1) with dimedone (2) and formaldehyde solution or paraformaldehyde, respectively. A mechanism is proposed based on the presence of a basic catalyst (triethylamine in this case) and the fact that single condensation intermediates are isolated prior to the cyclization leading to the final products.
