76161-51-8Relevant academic research and scientific papers
Thiourea catalysis of NCS in the synthesis of β-chloroethers
Bentley, Paul A.,Mei, Yujiang,Du, Juan
, p. 2653 - 2655 (2008/09/19)
Thiourea catalysis of olefin chlorination with NCS in an alcohol gives β-chloroethers with a very fast reaction of high yield.
Trichloroisocyanuric Acid as a Cohalogenating Reagent: An Efficient Transformation of Alkenes into Chlorohydrins, β-Chloroethers and β-Chloroacetates
Mendonca, Gabriela Fonseca,Sanseverino, Antonio Manzolillo,Mattos, Marcio C. S. de
, p. 45 - 48 (2007/10/03)
The preparation of diverse β-chloroethers, β-chloroacetates, and chlorohydrins is efficiently achieved under mild conditions by reaction of alkenes with trichloroisocyanuric acid (0.34 mol equiv) in alcohols (MeOH, EtOH, i-PrOH, t-BuOH), acetic acid or aqueous acetone, respectively.
Three-Component Reactions. VIII. Chlorination of Olefines in N-Methylpyrrolidone
Beger, J.,Jacobi, R.,Storch, A.,Ullmann, M.
, p. 394 - 400 (2007/10/02)
The chlorination of cyclohexene, styrene and 1-dodecene in NMP gives immonium-chlorides 5 reacting with water to β-chloralkyl-γ-N-methylaminobutyrat-hydrochlorides.With cyclohexene the reaction proceeds stereospecifically as trans-addition.From styrene there is only formed the Markovnikov product, and from dodecene a mixture of isomeres is obtained containing about 30percent of the anti-Markovnikov product.
