762299-36-5

Upstream product

• 119193-19-0 3-[(3R,4R)-3,4-dimethylpiperidin-4-yl]phenol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 205999-74-2 4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-1-tert-butyloxycarbonylpiperidine 

Downstream Products

• 762299-42-3 4(R)-(3-methoxycarbonylphenyl)-3(R),4-dimethyl-1-(2-trimethylsilylethyloxycarbonyl)piperidine 
• 762299-39-8 3-((3R,4R)-3,4-Dimethyl-piperidin-4-yl)-benzoic acid methyl ester 
• 762299-37-6 4(R)-(3-methoxycarbonylphenyl)-3(R),4-dimethyl-1-tertbutyloxycarbonylpiperidine 

Relevant academic research and scientific papers

Substituted piperidine compounds

Novel 3,4-disubstituted-4-aryl-piperidine compounds are disclosed. Pharmaceutical compositions containing the 3,4-disubstituted-4-aryl-piperidine compounds and methods of their pharmaceutical uses are also disclosed. The compounds disclosed are useful, in

trans-3,4-Dimethyl-4-(3-carboxamidophenyl)piperidines: A novel class of μ-Selective opioid antagonists

trans-3,4-Dimethyl-4-(3-carboxamidophenyl)piperidines constitute a novel class of μ opioid receptor antagonists. The CONH2 group was found to be an effective isostere of the phenolic OH moiety. Structure-activity relationships at the piperidine