76436-70-9Relevant academic research and scientific papers
SYNTHESIS OF IMMUNOSUPPRESIVE NEOGLYCOPROTEINS: BOVINE SERUM ALBUMIN COUPLED WITH 8-(HYDRAZINOCARBONYL)OCTYL 4- OR 6-O-&α-D-MANNOPYRANOSYL-&α-D-MANNOPYRANOSIDE
Wada, Kaoru,Chiba, Taku,Takei, Yutaka,Ishihara, Hideko,Hayashi, Hidetoshi,Onozaki, Kikuo
, p. 941 - 966 (2007/10/02)
Recombinant cytokines generated by bacteria, especially E.coli, are nonglycosylated.To investigate the effects of carbohydrates on their activities, we attempted to develop new cytokines by introduction of carbohydrates.As a model we synthesized neoglycop
Utilisation of Sulphur-containing Leaving Groups. Part 2. Monitored Reduction of Carboxylic Acids into Alcohols or Aldehydes via 3-Acylthiazolidine-2-thiones by Sodium Borohydride or Di-isobutylaluminium Hydride
Nagao, Yoshimitsu,Kawabata, Kohji,Seno, Kaoru,Fujita, Eiichi
, p. 2470 - 2473 (2007/10/02)
3-Acylthiazolidine-2-thiones (2) have been prepared by three methods, and treated with di-isobutylaluminium hydride or sodium borohydride to give aldehyde or alcohol in high yield, respectively.The original yellow colour disappears when reduction is finished, enabling the reaction to be monitored.The high reactivity of the carbonyl group in amide (2) was briefly discussed.
