76439-40-2Relevant articles and documents
Preparation method for pyrazole
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Paragraph 0011; 0012; 0013; 0014; 0015; 0016; 0023; 0024, (2017/08/26)
The invention relates to a preparation method for pyrazole, belonging to the field of organic chemistry. The preparation method disclosed in the invention realizes preparation of pyrazole through a cyclization reaction of N-alkylated phenylsulfonylhydrazone with terminal alkyne. The reaction has good function group tolerance and high yield and is applicable to a wide range of substrates.
Regioselective synthesis of 1,3,5-Trisubstituted Pyrazoles from N-Alkylated Tosylhydrazones and terminal Alkynes
Kong, Yuanfang,Tang, Meng,Wang, Yun
supporting information, p. 576 - 579 (2014/04/03)
An efficient synthesis of 1,3,5-trisubstituted pyrazoles from Nalkylated tosylhydrazones and terminal alkynes was developed. The protocol was applied to a wide range of substrates and demonstrated excellent tolerance to a variety of substituents, includin
Efficient one-pot synthesis of substituted pyrazoles
Tang, Meng,Zhang, Fu-Min
, p. 1427 - 1433 (2013/02/25)
An efficient, one-pot synthesis of substituted pyrazoles from enones, hydrazides, and halides was developed. In comparison with the classical Knorr pyrazole synthesis, this methodology gave a different type of product (R 3≥R5). A range of substituted pyrazoles were prepared in good to high yields with complete regioselectivity.