76529-98-1Relevant academic research and scientific papers
Fluorescence quenched quinone methide based activity probes - A cautionary tale
Sellars, Jonathan D.,Landrum, Marie,Congreve, Aileen,Dixon, David P.,Mosely, Jackie A.,Beeby, Andrew,Edwards, Robert,Steel, Patrick G.
experimental part, p. 1610 - 1618 (2010/07/04)
A carbamate linked quenching group coupled with a pro-quinone methide reactive core provides an effective tool for studying enzyme function without problems associated with background fluorescence from unreacted probe. However, the relatively slow fragmentation of the carbamate linkage in such a strategy may cause problems of loss of signal or a decoupling of enzyme activity and labelling.
ARYL AND HETEROARYLMETHOXYPHENYL INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS
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, (2008/06/13)
The present invention relates to a compound of the formula or a pharmaceutically acceptable salt thereof wherein W is selected from optionally substituted pyridyl, naphthyl, and quinolyl; which inhibits lipoxygenase enzyme activity and leukotriene biosynt
Polypeptide compound and a process for preparation thereof
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, (2008/06/13)
A polypeptide compound having antimicrobial activity of the following general formula: STR1 wherein R1 is hydrogen or acyl group, R2 is hydroxy or acyloxy, R3 is hydroxysulfonyloxy, and R4 is hydrogen or carbamoyl, with proviso that R1 is not palmitoyl, when R2 is hydroxy, R3 is hydroxysulfonyloxy and R4 is carbamoyl, and a pharmaceutically acceptable salt thereof.
HYPERVALENT IODINE IN ORGANIC SYNTHESIS. A NEW ROUTE TO α-FUNCTIONALIZED CARBOXYLATE ESTERS.
Moriarty, Robert M.,Hu, Henry
, p. 2747 - 2750 (2007/10/02)
Aryl and alkylcarboxylate esters are converted into the corresponding α-hydroxy acids or α-alkoxyesters upon treatment with C6H5I(OAc)2 and base in the appropriate solvent.
