765298-04-2

Basic information

• Product Name: 3-PYRIDINEACETONITRILE, 6-(TRIFLUOROMETHYL)-
• Synonyms: 3-PYRIDINEACETONITRILE, 6-(TRIFLUOROMETHYL)-;RARECHEM AL MP 0326;2-(Trifluoromethyl)pyridine-5-acetonitrile;2-(6-(trifluoromethyl)pyridin-3-yl)acetonitrile;3-Pyridineacetonitrile, 6-(Trifluoromethyl)-(WX684039)
• CAS NO: 765298-04-2
• Molecular Formula: C8H5F3N2
• Molecular Weight: 186.14
• Mol File: 765298-04-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 243.6 °C at 760 mmHg
• Flash Point: 101.1 °C
• Appearance: /
• Density: 1.307 g/cm³
• Vapor Pressure: 0.0317mmHg at 25°C
• Refractive Index: 1.457
• PKA: -0.51±0.22(Predicted)
• CAS DataBase Reference: 3-PYRIDINEACETONITRILE, 6-(TRIFLUOROMETHYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PYRIDINEACETONITRILE, 6-(TRIFLUOROMETHYL)-(765298-04-2)
• EPA Substance Registry System: 3-PYRIDINEACETONITRILE, 6-(TRIFLUOROMETHYL)-(765298-04-2)

Safety Data

• Hazardous Substances Data: 765298-04-2(Hazardous Substances Data)

Usage

General Description

3-Pyridineacetonitrile, 6-(trifluoromethyl)- is a chemical compound with the molecular formula C8H5F3N2. It consists of a pyridine ring with a cyano group and a trifluoromethyl group attached at the 3rd and 6th positions, respectively. 3-Pyridineacetonitrile, 6-(trifluoromethyl)- is a versatile building block in organic synthesis and is commonly used as a reagent in the production of pharmaceuticals and agrochemicals. It has also been studied for its potential use in the development of new materials and as a precursor for the synthesis of various heterocyclic compounds. Additionally, 3-Pyridineacetonitrile, 6-(trifluoromethyl)- has been found to exhibit insecticidal properties, making it of interest for use in pest control products.

InChI:InChI=1/C8H5F3N2/c9-8(10,11)7-2-1-6(3-4-12)5-13-7/h1-2,5H,3H2

Upstream product

• 223463-13-6 2-iodo-5-bromopyridine 
• 349-94-0 5-chloro-2-(trifluoromethyl)pyridine 
• 624-28-2 2,5-dibromopyridine 
• 936841-73-5 5-fluoro-2-(trifluoromethyl)pyridine 
• 436799-32-5 5-bromo-2(trifluoromethyl)pyridine 
• 1616257-35-2 methyl 2-cyano-2-(6-(trifluoromethyl)pyridin-3-yl)acetate 
• 386715-33-9 3-chloromethyl-6-(trifluoromethyl)pyridine 
• 386704-04-7 6-(trifluoromethyl)pyridin-3-ylmethanol 
• 221313-10-6 methyl 6-(trifluoromethyl)pyridine-3-carboxylate 
• 231291-22-8 6-trifluoromethylnicotinic acid 
• 1257088-58-6 ethyl 2-cyano-2-[6-(trifluoromethyl)-3-pyridyl]acetate 
• 773837-37-9 sodium cyanide 

Relevant articles and documents

Application of Vinamidinium Salt Chemistry for a Palladium Free Synthesis of Anti-Malarial MMV048: A bottom-Up Approach

MMV390048 (1) is a clinical compound under investigation for antimalarial activity. A new synthetic route was developed which couples two aromatic fragments while forming the central pyridine ring over two steps. This sequence takes advantage of raw materials used in the existing etoricoxib supply chain and eliminates the need for palladium catalysts, which were projected to be major cost-drivers.

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