7659-29-2

Usage

Uses

Used in Pharmaceutical Industry:
3,5-DINITROCATECHOL is used as an anti-inflammatory agent for the treatment of rheumatoid arthritis and osteoarthritis. Its chemical structure allows it to modulate inflammatory pathways and provide relief from pain and swelling associated with these conditions.
Used in Chemical Research:
3,5-DINITROCATECHOL is used as a research compound in the development of new drugs and pharmaceuticals. Its unique chemical properties make it a valuable tool for studying various biological processes and potential therapeutic targets.
Used in Environmental Applications:
3,5-DINITROCATECHOL can be used in environmental applications, such as water and soil treatment, due to its ability to bind with and neutralize harmful substances. This can help in the remediation of contaminated sites and the protection of ecosystems.

Biological Activity

Potent and selective inhibitor of catechol-O-methyl-transferase.

InChI:InChI=1/C6H4N2O6/c9-5-2-3(7(11)12)1-4(6(5)10)8(13)14/h1-2,9-10H/p-2

Upstream product

• 4097-63-6 2-methoxy-4,6-dinitrophenol 
• 635-67-6 dimethyl phthalate 
• 89563-21-3 2,4-dinitro-6-pentafluorophenyliodoniophenolate 
• 89563-18-8 2,4-dinitro-6-phenyliodonium phenolate 
• 51-28-5 2,4-Dinitrophenol 
• 7647-01-0 hydrogenchloride 
• 89563-26-8 (2-Hydroxy-3,5-dinitro-phenyl)-phenyl-iodonium; chloride 
• 88-85-7 dinoseb 

Downstream Products

• 59820-95-0 5,7-dinitro-2,3-dihydro-benzo[1,4]dioxine 
• 70187-40-5 2-(2-hydroxy-3,5-dinitro-phenoxy)-ethanol 
• 98134-91-9 3,5-diamino-pyrocatechol 
• 860690-95-5 5,7-Diacetamido-benzdioxan-(1,4) 
• 116313-88-3 1,2-dipropionyloxy-3,5-dinitrobenzene 
• 116313-83-8 1,2-diacetoxy-3,5-dinitro-benzene 
• 154329-19-8 Pt(O₂C₆H₂-3,5-(NO₂)2)(P(CH₃)2(C₆H₅))2 
• 154329-18-7 Pt(O₂C₆H₂-3,5-(NO₂)2)(PCH₃(C₆H₅)2)2 

Relevant academic research and scientific papers

On the mechanism of the Elbs peroxydisulfate oxidation and a new peroxide rearrangement

Semiempirical calculations show that the intermediate formed by reaction between peroxydisulfate anion and the phenolate ion (the Elbs oxidation) is the species resulting from reaction of the tautomeric carbanion rather than the one resulting from attack by the oxyanion. This is confirmed by synthesis of the latter intermediate by reaction between Caro's acid dianion (peroxymonosulfate) and some nitro-substituted fluorobenzenes. This intermediate rearranges preferentially to give the phenol ortho-sulfate rather than the para-sulfate characteristic of the Elbs oxidation. This reaction of an arylperoxysulfate to give a phenol ortho-sulfate is a new rearrangement.

Photocatalytic activity of TiO2 supported SiO2-Al2O3 aerogels prepared from industrial fly ash

A ternary composite of TiO2 and a SiO2-Al2O3 aerogel with good photocatalytic activity was prepared by a simple sol-gel method with TiO2 nanoparticles and SiO2-Al2O3 aerogels derived from industrial fly ash. The structural features of the TiO2/SiO2-Al2O3 aerogel composite were investigated by X-ray powder diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, gas adsorption measurements and diffuse reflectance UV-visible spectroscopy. The optimal conditions for photocatalytic degradation of 2-sec-butyl-4,6-dinitrophenol (DNBP), included an initial DNBP concentration of 0.167 mmol/L at pH = 4.86 with a catalyst concentration of 6 g/L, under visible light irradiation for 5 h. A plausible mechanism is proposed for the photocatalytic degradation of DNBP. Our composite showed higher photocatalytic activity for DNBP degradation than that of pure TiO2. This indicates that this material can serve as an efficient photocatalyst for degradation of hazardous organic pollutants in wastewater.

PHARMACOLOGICALLY ACTIVE COMPOUNDS, METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME

Pharmacologically active catechol derivatives of formula I I wherein R1 and R2 independently comprise hydrogen, alkyl, acyl, optionally substituted aroyl, lower alkylsulfonyl or alkylcabamoyl or taken together form a lower alkylidene or cycloalkylidene, X comprises an electronegative substituent such as halogen, nitro, cyano, lower alkylsulfonyl, sulfonamido, aldehyde, caboxyl or trifluoromethyl and R3 comprises hydrogen, halogen, hydroxy alkyl, amino, nitro, cyano, trifluoromethyl, lower alkylsulfonyl, sulfonamide, aldehyde, alkyl carbonyl, aralkylidene carbonyl or carboxyl or a group selected from wherein R4 comprises hydrogen, alkyl, cyano, carboxyl or acyl and R5 comprises hydrogen, cyano, carboxyl, alkoxycarbonyl, carboxyalkenyl, nitro, acyl, optionally substituted aroyl or heteroaroyl, hydroxyalkyl or carboxyalkyl or R4 and R5 together form a five to seven membered substituted cycloalkanone ring; -(CO)n(CH2)m-COR wherein n is 0-1 and m is 0-7 and R comprises hydroxy, alkyl, carboxyalkyl, optionally substituted alkene, alkoxy or optionally substituted amino; wherein R8 and R9 independently comprise hydrogen or one of the following optionally substituted groups; alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl, or together form an optionally substituted piperidyl group; -NH-CO-R10 wherein R10 comprises a substituted alkyl group

Synthesis and Reactivity of 2-Oxidodiaryliodonium Zwitterions

The direct synthesis of three new 2-oxidoaryliodonium zwitterions from phenols and aryliodine(III) bistrifluoroacetate and their reaction with nucleophiles and electrophiles are reported.Especially noteworthy is the reactivity of 2-methoxy-3,5-dinitrophenyl(phenyl)iodonium tetrafluoroborate (15) which is hydrolysed by water and solvolysed by alcohols at room temperature.