765948-78-5

Basic information

• Product Name: 2,3-DIHYDRO-1H-ISOINDOL-1-ONE-4-BORONIC ACID PINACOL ESTER
• Synonyms: 1-Isoindolinone-4-boronic acid pinacol ester;1H-Isoindol-1-one, 2,3-dihydro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-isoindol-1-one;(1-Oxo-2,3-dihydro-1H-isoindol-4-yl)boronic acid, pinacol ester;4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-isoindol-1-one;1H-Isoindol-1-one-4-boronic acid pinacol ester;2,3-DIHYDRO-1H-ISOINDOL-1-ONE-4-BORONIC ACID PINACOL ESTER;4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one
• CAS NO: 765948-78-5
• Molecular Formula: C₁₄H₁₈BNO₃
• Molecular Weight: 259.1086
• Mol File: 765948-78-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: 189-191 °C(Solv: hexane (110-54-3))
• Boiling Point: 483.191 °C at 760 mmHg
• Flash Point: 246.025 °C
• Appearance: /
• Density: 1.163 g/cm³
• Storage Temp.: 2-8°C
• PKA: 13.82±0.20(Predicted)
• CAS DataBase Reference: 2,3-DIHYDRO-1H-ISOINDOL-1-ONE-4-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-1H-ISOINDOL-1-ONE-4-BORONIC ACID PINACOL ESTER(765948-78-5)
• EPA Substance Registry System: 2,3-DIHYDRO-1H-ISOINDOL-1-ONE-4-BORONIC ACID PINACOL ESTER(765948-78-5)

Safety Data

• Hazardous Substances Data: 765948-78-5(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1H-isoindol-1-one-4-boronic acid pinacol ester is a boronic acid derivative used in organic synthesis as a building block for the preparation of various pharmaceutical compounds and agrochemicals. It is commonly used in the Suzuki-Miyaura cross-coupling reaction to form carbon-carbon bonds. 2,3-DIHYDRO-1H-ISOINDOL-1-ONE-4-BORONIC ACID PINACOL ESTER contains a boronic acid moiety, which is known for its reactivity with certain functional groups in organic molecules, making it a valuable tool in synthetic chemistry. It is also a stable and easily handled solid, making it a convenient reagent for various chemical transformations.

Upstream product

• 337536-14-8 methyl 3-bromo-2-(bromomethyl)benzoate 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 21900-48-1 3-bromo-2-methylbenzoic acid chloride 
• 99548-54-6 methyl 3-bromo-2-methylbenzoate 
• 73183-34-3 bis(pinacol)diborane 
• 337536-15-9 4-bromo-2,3-dihydro-isoindol-1-one 

Downstream Products

• 765948-85-4 4-(4-amino-2-chlorophenyl)-1-isoindolinone 
• 765948-88-7 4-(4-amino-3,5-dimethyl-phenyl)-2,3-dihydro-isoindol-1-one 
• 765948-81-0 4-(4-amino-2-methylphenyl)-1-isoindolinone 
• 765948-87-6 4-(4-amino-3-ethylphenyl)-1-isoindolinone 
• 765948-83-2 4-[4-amino-2-(trifluoromethyl)phenyl]-2,3-dihydro-isoindol-1-one 
• 765948-82-1 4-(4-amino-3-methyl-phenyl)-2,3-dihydro-isoindol-1-one 
• 765948-79-6 4-(4-amino-2-fluorophenyl)-1-isoindolinone 
• 765948-86-5 4-(4-amino-3-chlorophenyl)-1-isoindolinone 
• 765948-84-3 4-[4-amino-3-(trifluoromethyl)phenyl]-1-isoindolinone 
• 765948-80-9 4-(4-amino-3-fluorophenyl)-1-isoindolinone 

Relevant articles and documents

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