1007862-01-2

Upstream product

• 112898-33-6 3-(2,5-difluorophenyl)acrylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 67-56-1 methanol 

Downstream Products

• 767355-26-0 trans-3-(2,5-difluoro-phenyl)-prop-2-en-1-ol 
• 1245078-62-9 3-(2,5-difluorophenyl)-4-nitrobutyric acid methyl ester 
• 1197396-81-8 (1R)-1-[(4-{[(2E)-3-(2,5-difluorophenyl)-2-propen-1-yl]amino}-1-piperidinyl)methyl]-1,2-dihydro-4H,9H-imidazo[1,2,3-ij]-1,8-naphthyridine-4,9-dione 
• 1073495-60-9 (1R)-1-[(4-{[(2E)-3-(2,5-difluorophenyl)-2-propen-1-yl]amino}-1-piperidinyl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one 
• 872263-26-8 (E)-3-(2,5-difluorophenyl)acrylaldehyde 

Relevant academic research and scientific papers

COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS

The present invention is directed to therapeutic compounds which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes.

COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS

The present invention is directed to therapeutic compotmds of the following formula (I) which have activity as agonists of GPR 119 and are useful for the treatment of metabolic disorders including type II diabetes.

TRICYCLIC NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIALS

Compounds of Formula (I) or a pharmaceutically acceptable salt or N-oxide thereof; Formula (I) (relative stereochemistry shown) wherein: Z1, Z2 , L are as defined, U represents a cyclic group selected from: phenyl, pyridyl, pyridazin

TRICYCLIC COMPOUNDS AS ANTIBACTERIALS

Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.