7682-15-7

Basic information

• Product Name: AC-DL-NVA-OH
• Synonyms: ACETYL-DL-NORVALINE;ACETYL-DL-2-AMINOVALERIC ACID;AC-DL-NVA-OH;N-ALPHA-ACETYL-DL-NORVALINE;N-ACETYL-DL-NORVALINE;N-Acetyl-DL-norvaline,98%;2-Acetamidopentanoic acid;NSC 203439
• CAS NO: 7682-15-7
• Molecular Formula: C₇H₁₃NO₃
• Molecular Weight: 159.18
• Mol File: 7682-15-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 111.0-112.5 °C
• Boiling Point: 371.8ºC at 760 mmHg
• Flash Point: 178.7ºC
• Appearance: /
• Density: 1.097g/cm3
• Vapor Pressure: 1.5E-06mmHg at 25°C
• Refractive Index: 1.458
• PKA: 3.69±0.10(Predicted)
• CAS DataBase Reference: AC-DL-NVA-OH(CAS DataBase Reference)
• NIST Chemistry Reference: AC-DL-NVA-OH(7682-15-7)
• EPA Substance Registry System: AC-DL-NVA-OH(7682-15-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 7682-15-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H13NO3/c1-3-4-6(7(10)11)8-5(2)9/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)

Upstream product

• 760-78-1 2-aminopentanoic acid 
• 108-24-7 acetic anhydride 
• 1896-62-4 (E)-benzalacetone 
• 106-88-7 ethyloxirane 
• 60-35-5 acetamide 
• 201230-82-2 carbon monoxide 
• 82518-89-6 acetylamino-propyl-malonic acid diethyl ester 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 123-72-8 butyraldehyde 
• 187737-37-7 propene 
• 627-27-0 homoalylic alcohol 
• 504-61-0 (E)-but-2-enol 
• 692-33-1 N-allylacetamide 

Downstream Products

• 1575837-19-2 (3R,4R)-3-benzamido-2,5-dioxo-4-phenyl-3-propylpyrrolidin-1-yl acetate 
• 1242985-40-5 (R)-4-((S)-1-(furan-2-yl)-3-oxobutyl)-2-phenyl-4-propyloxazol-5(4H)-one 
• 1242985-41-6 (R)-4-((R)-3-oxo-1,3-diphenylpropyl)-2-phenyl-4-propyloxazol-5(4H)-one 
• 1242985-37-0 (R)-4-((R)-1-(4-chlorophenyl)-3-oxobutyl)-2-phenyl-4-propyloxazol-5(4H)-one 
• 1242985-35-8 (R)-4-((R)-3-oxo-1-phenylbutyl)-2-phenyl-4-propyloxazol-5(4H)-one 
• 498-18-0 D-norvaline 
• 6600-40-4 L-norvaline 
• 399035-16-6 N-[1-(4-methyl-benzoyl)-butyl]-acetamide 
• 6600-40-4 L-Norvaline 
• 57357-56-9 N-acetyl-D-norvaline 
• 2013-12-9 D-norvaline 

Relevant articles and documents

Efficient kinetic resolution of amino acids catalyzed by lipase AS 'Amano' via cleavage of an amide bond

Herein the efficient kinetic resolution of non-natural alpha-amino acids catalyzed by lipase AS 'Amano' via cleaving the amide bond is reported. The starting materials were the corresponding amino acid amides and the amino acids were generated with ees of up to 99% with E values of >600. These results indicated that the lipase AS 'Amano' could be a powerful amide hydrolase for the kinetic resolution of amino acid starting from the corresponding amino acid amides.

Palladium-catalyzed amidocarbonylation improved by recyclable ionic liquids

Two types of ionic liquids (halide anion ionic liquids and Brensted acidic ionic liquids) were first applied to improve the palladium-catalyzed amidocarbonylation. Both the palladium catalyst and the ionic liquids could be recycled at least five times without significant loss in catalytic activity. Georg Thieme Verlag Stuttgart.

STUDIES ON HYDROCARBOXYLATION OF N-ACETYLIMINES, ENAMINES AND ALLYLAMINES.

Treatment of an amide with an aldehyde in the presence of Co2(CO)8/CO/H2 results in N-acyl-α-amino acids. The scope and limitations of this reaction are explored