77367-70-5

Basic information

• Product Name: 2-benzyloxycyclohepta-2,4,6-trienone
• Synonyms: 2-benzyloxycyclohepta-2,4,6-trienone
• CAS NO: 77367-70-5
• Molecular Weight: 212.248
• Mol File: 77367-70-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-benzyloxycyclohepta-2,4,6-trienone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxycyclohepta-2,4,6-trienone(77367-70-5)
• EPA Substance Registry System: 2-benzyloxycyclohepta-2,4,6-trienone(77367-70-5)

Safety Data

• Hazardous Substances Data: 77367-70-5(Hazardous Substances Data)

Upstream product

• 533-75-5 2-hydroxy-2,4,6-cycloheptatrien-1-one 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 533-75-5 2-hydroxy-2,4,6-cycloheptatrien-1-one 
• 77367-77-2 3-benzyl-tropolone 
• 77367-84-1 5-benzyltropolone 
• 75-18-3 dimethylsulfide 
• 100-52-7 benzaldehyde 
• 62412-12-8 2-(benzyloxy)-7-bromocyclohepta-2,4,6-trien-1-one 
• 1946-74-3 2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one 
• 36841-98-2 2-cyclohexylcyclohepta-2,4,6-trien-1-one 
• 126385-38-4 3-Benzyl-2-methoxy-cyclohepta-2,4,6-trienone 
• 126385-39-5 5-Benzyl-2-methoxy-cyclohepta-2,4,6-trienone 
• 126385-37-3 2-benzyl-7-methoxy-tropone 

Relevant articles and documents

TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS

Disclosed are a series of compounds or their tautomers having a general structure represented by Formula (la), (lb), (Ila), (lIb), or (lIc) and pharmaceutically acceptable salts thereof. The present disclosure also relates to pharmaceutical compositions comprising said compounds or tautomers. The present disclosure further relates to a method of treating a disease or condition associated with iron dysregulation or dysfunctional iron homeostasis comprising administering to a subject in need thereof a therapeutically effective amount of Formula (la), (lb), (Ila), (lIb), or (lIc) compounds or tautomers.

Synthesis and biological evaluation of O-alkylated tropolones and related α-ketohydroxy derivatives as ribonucleotide reductase inhibitors

A series of O-alkylated tropolones and related α-ketohydroxy compounds were evaluated for their biological activities and were shown to present an expected ribonucleotide reductase inhibition and cytotoxicity against some cancer cell lines but no antitubulin activity. Pharmacomodulation studies were realised to understand and enhance the observed activities. These original benzylic, heterocyclic and allylic compounds have been synthesised by a phase-transfer catalysed O-alkylation developed in our laboratories.

Asymmetric induction with cyclodextrins: Photocyclization of tropolone alkyl ethers

Employing the photobehavior of tropolone alkyl ethers as the probe, we have established that cyclodextrins could as a serve as medium to bring about enantioselective photoreactions. The enantioselectivity observed in this study is moderate at best. The enantioselectivity observed in the solid state in comparison to aqueous solution suggests that a rigid environment may be essential to achieve chiral induction during photoreactions of organic molecules. In this context the much higher enantioselectivity observed for the same systems within zeolites is noteworthy. (C) 2000 Elsevier Science Ltd.