7751-67-9

Basic information

• Product Name: (3-Methyl-2-oxobutyl)phosphonic acid diethyl ester
• Synonyms: (3-Methyl-2-oxobutyl)phosphonic acid diethyl ester;Diethyl (3-methyl-2-oxobutyl)phosphonate;Diethyl (2-oxo-3-methylbutyl)phosphonate
• CAS NO: 7751-67-9
• Molecular Formula: C₉H₁₉O₄P
• Molecular Weight: 222
• Mol File: 7751-67-9.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Density: 1.050
• CAS DataBase Reference: (3-Methyl-2-oxobutyl)phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-Methyl-2-oxobutyl)phosphonic acid diethyl ester(7751-67-9)
• EPA Substance Registry System: (3-Methyl-2-oxobutyl)phosphonic acid diethyl ester(7751-67-9)

Safety Data

• Hazardous Substances Data: 7751-67-9(Hazardous Substances Data)

Usage

General Description

(3-Methyl-2-oxobutyl)phosphonic acid diethyl ester is a chemical compound with the molecular formula C9H19O5P. It is an organic phosphonate compound that is commonly used as a chelating agent in various industrial processes, including water treatment, metal processing, and cleaning products. It is known for its ability to bind and remove metal ions from aqueous solutions, making it useful in preventing scale and corrosion in water systems. (3-Methyl-2-oxobutyl)phosphonic acid diethyl ester is also used as a stabilizer and as a component in the production of various polymers. Additionally, it has potential applications in the pharmaceutical and agricultural industries. However, it is important to handle this compound with care, as it can potentially be hazardous if not properly managed.

Upstream product

• 3167-63-3 diethyl chloromethylphosphonate 
• 78-84-2 isobutyraldehyde 
• 683-08-9 Diethyl methylphosphonate 
• 79-30-1 isobutyryl chloride 
• 3201-84-1 3-methyl-1,2-butadienephosphonic acid diethyl ester 
• 19967-55-6 1-bromo-3-methyl-2-butanone 
• 122-52-1 triethyl phosphite 
• 76002-26-1 2-Chlor-2-isopropyloxiran 
• 17687-63-7 1-chloro-3-methylbutan-2-one 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 18362-64-6 2,6-dimethyl-3,5-heptanedione 
• 762-04-9 phosphonic acid diethyl ester 
• 563-80-4 3-methyl-butan-2-one 

Downstream Products

• 301695-61-4 (5α,7α,24R)-7,24-dihydroxy-3-ketocholestane 
• 208254-13-1 (5α,7α)-3-spiro-2'-(1',3'-dioxolan)-24-oxocholest-22-en-7-yl benzoate 

Relevant articles and documents

Synthesis of 3&β,29-Dihydroxystigmasta-5,24(28)(E)-dien-7-one

The synthesis of 3β,29-dihydroxystigmasta-5,24(28)(E)-dien-7-one from 3β-acetoxy-22,23-dinorcholenaldehyde has been achieved in an overall yield of 7 percent..Witting reaction of the aldehyde and diethyl (3-methyl-2-oxobutyl)phosphonate anion gave 3β-acetoxycholesta-5,22-dien-24-one which was hydrogenated selectively, and the saturated ketone was allowed to react with the anion of diethyl (cyanomethyl)phosphonate.The resulting nitrile was reduced via the alehyde to 29-hydroxyfucosterol by using DIBAL-H.Acetylation of this diol and oxidation with chromium trioxide-3,5-dimethylpyrazole afforded the 7-ketone.Mild hydrolysis of the acetate groups completed the synthesis.

Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds

A method is described for stereoselectively reducing an unsaturated alkyl ketone substituent attached to a fused ring base. In this method, the unsaturated alkyl ketone reacts with a chiral oxazaborolidine reagent. This reaction stereoselectively reduces

One pot synthesis of mono- and spirocyclic α-phosphonato-α,β- unsaturated cycloenones

A one pot ozonolysis/intramolecular aldol condensation(with the aid of T(s)OH and Et3N as catalysts) of β-keto-ω-alkenylphosphonates provided the α-phosphonato-α,β-unsaturated cycloenone with good yields.