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Usage

Uses

Used in Water Treatment Industry:
(3-Methyl-2-oxobutyl)phosphonic acid diethyl ester is used as a chelating agent for preventing scale and corrosion in water systems due to its ability to bind metal ions.
Used in Metal Processing Industry:
(3-Methyl-2-oxobutyl)phosphonic acid diethyl ester is used as a chelating agent for removing metal ions from aqueous solutions, which helps in metal processing.
Used in Cleaning Products Industry:
(3-Methyl-2-oxobutyl)phosphonic acid diethyl ester is used as a chelating agent in cleaning products to remove metal ions and prevent scale buildup.
Used in Polymer Production:
(3-Methyl-2-oxobutyl)phosphonic acid diethyl ester is used as a stabilizer and a component in the production of various polymers.
Used in Pharmaceutical Industry:
(3-Methyl-2-oxobutyl)phosphonic acid diethyl ester has potential applications in the pharmaceutical industry, although specific uses are not mentioned in the provided materials.
Used in Agricultural Industry:
(3-Methyl-2-oxobutyl)phosphonic acid diethyl ester has potential applications in the agricultural industry, although specific uses are not mentioned in the provided materials.
It is important to handle (3-Methyl-2-oxobutyl)phosphonic acid diethyl ester with care, as it can potentially be hazardous if not properly managed.

Upstream product

• 3167-63-3 diethyl chloromethylphosphonate 
• 78-84-2 isobutyraldehyde 
• 3201-84-1 3-methyl-1,2-butadienephosphonic acid diethyl ester 
• 19967-55-6 1-bromo-3-methyl-2-butanone 
• 122-52-1 triethyl phosphite 
• 76002-26-1 2-Chlor-2-isopropyloxiran 
• 18362-64-6 2,6-dimethyl-3,5-heptanedione 
• 762-04-9 phosphonic acid diethyl ester 
• 563-80-4 3-methyl-butan-2-one 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 17687-63-7 1-chloro-3-methylbutan-2-one 
• 683-08-9 Diethyl methylphosphonate 
• 79-30-1 isobutyryl chloride 

Downstream Products

• 208254-13-1 (5α,7α)-3-spiro-2'-(1',3'-dioxolan)-24-oxocholest-22-en-7-yl benzoate 
• 301695-61-4 (5α,7α,24R)-7,24-dihydroxy-3-ketocholestane 

Relevant academic research and scientific papers

Synthesis of 3&β,29-Dihydroxystigmasta-5,24(28)(E)-dien-7-one

The synthesis of 3β,29-dihydroxystigmasta-5,24(28)(E)-dien-7-one from 3β-acetoxy-22,23-dinorcholenaldehyde has been achieved in an overall yield of 7 percent..Witting reaction of the aldehyde and diethyl (3-methyl-2-oxobutyl)phosphonate anion gave 3β-acetoxycholesta-5,22-dien-24-one which was hydrogenated selectively, and the saturated ketone was allowed to react with the anion of diethyl (cyanomethyl)phosphonate.The resulting nitrile was reduced via the alehyde to 29-hydroxyfucosterol by using DIBAL-H.Acetylation of this diol and oxidation with chromium trioxide-3,5-dimethylpyrazole afforded the 7-ketone.Mild hydrolysis of the acetate groups completed the synthesis.

Silver-Catalyzed Oxidative C(sp3)?P Bond Formation through C?C and P?H Bond Cleavage

The silver-catalyzed oxidative C(sp3)?H/P?H cross-coupling of 1,3-dicarbonyl compounds with H-phosphonates, followed by a chemo- and regioselective C(sp3)?C(CO) bond-cleavage step, provided heavily functionalized β-ketophosphonates. This novel method based on a readily available reaction system exhibits wide scope, high functional-group tolerance, and exclusive selectivity.

Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds

A method is described for stereoselectively reducing an unsaturated alkyl ketone substituent attached to a fused ring base. In this method, the unsaturated alkyl ketone reacts with a chiral oxazaborolidine reagent. This reaction stereoselectively reduces

One pot synthesis of mono- and spirocyclic α-phosphonato-α,β- unsaturated cycloenones

A one pot ozonolysis/intramolecular aldol condensation(with the aid of T(s)OH and Et3N as catalysts) of β-keto-ω-alkenylphosphonates provided the α-phosphonato-α,β-unsaturated cycloenone with good yields.

Preparation of 1-aminoalkylphosphonic acids and 2-aminoalkylphosphonic acids by reductive amination of oxoalkylphosphonates

By reacting dialkyl 1-oxo- or 2-oxoalkylphosphonates with benzhydrylamine followed by reduction with triacetoxyborohydride and acid hydrolysis gave corresponding aminoalkylphosphonic acids with satisfactory yields. The use of benzylamine, α-methylbenzylamine and tritylamine was unsuccessful in the case of dialkyl 1-oxoalkylphosphonates whereas conversion of 2-oxoalkylphosphonates was also achieved although with lower yields.

Reaction of 2-Chlorooxiranes with Phosphites and Phosphanes: A New Route to β-Carbonylphosphonic Esters and -phosphonium Salts

Reaction of alkylsubstituted 2-chlorooxiranes 6 with trialkyl phosphites 11 gives β-carbonylphosphonic diesters (12a, b, 15a, b, 20a, 21a), free of isomeric enol phosphates or α,β-epoxyphosphonates. 2-Chloro-2-(chloromethyl)oxirane (6c) undergoes with 11 an Arbusov reaction followed by a Perkow reaction ( -> 18 -> 17).The limitation of the method is probed with sterically crowded substituents in 3-position of 6. 6b yields with triphenylphosphane a β-ketophosphonium salt (23), which can be converted to a keto-ylide (24).

PHOSPHOR- UND SCHWEFELSUBSTITUIERTE ALLENE IN DER SYNTHESE I : EINFACHE SYNTHESE VON β-KETOPHOSPHONATEN AUS 1-ALKIN-3-OLEN

Allenic phosphonates, readily accessible from 1-alkin-3-ols, the addition products of 1-alkines to aldehydes or ketones, can be transformed to β-ketophosphonates by nucleophilic addition of diethylamine and subsequent hydrolysis of the formed enamines.

β-Ketophosphonsaeureester aus α-chloroxiranen

β-Ketophosphonic ester can be obtained by the treatment of α-chloroepoxides with trialkylphosphites.