77669-23-9

Basic information

• Product Name: (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)quinoline
• CAS NO: 77669-23-9
• Molecular Weight: 275.307
• Mol File: 77669-23-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)quinoline(77669-23-9)
• EPA Substance Registry System: (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)quinoline(77669-23-9)

Safety Data

• Hazardous Substances Data: 77669-23-9(Hazardous Substances Data)

Upstream product

• 91-63-4 2-methylquinoline 
• 120-57-0 piperonal 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 93-10-7 quinoline-2-carboxylic acid 
• 4491-33-2 ethyl quinoline-2-carboxylate 
• 5470-96-2 quinoline 2-carbaldehyde 
• 58005-36-0 (benzo[d][1,3]dioxol-5-ylmethyl)triphenylphosphonium bromide 
• 2606-51-1 3,4-Methylenedioxybenzyl bromide 
• 495-76-1 piperonol 
• 772-03-2 2-vinylquinoline 
• 5876-51-7 5-iodo-1,3-benzodioxole 
• 22214-31-9 (E)-4-(benzo[d][1,3]dioxol-5-yl)but-3-en-2-one 
• 552-89-6 2-nitro-benzaldehyde 
• 2620-50-0 1,3-benzodioxol-5-ylmethyl amine 

Downstream Products

• 375395-24-7 2-(2-(benzo[d][1,3]-dioxol-5-yl)ethyl)-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

Water-Sculpting of a Heterogeneous Nanoparticle Precatalyst for Mizoroki-Heck Couplings under Aqueous Micellar Catalysis Conditions

Powdery, spherical nanoparticles (NPs) containing ppm levels of palladium ligated by t-Bu3P, derived from FeCl3, upon simple exposure to water undergo a remarkable alteration in their morphology leading to nanorods that catalyze Mizoroki-Heck (MH) couplings. Such NP alteration is general, shown to occur with three unrelated phosphine ligand-containing NPs. Each catalyst has been studied using X-ray photoelectron spectroscopy (XPS), energy-dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), and cryogenic transmission electron microscopy (cryo-TEM) analyses. Couplings that rely specifically on NPs containing t-Bu3P-ligated Pd occur under aqueous micellar catalysis conditions between room temperature and 45 °C, and show broad substrate scope. Other key features associated with this new technology include low residual Pd in the product, recycling of the aqueous reaction medium, and an associated low E Factor. Synthesis of the precursor to galipinine, a member of the Hancock family of alkaloids, is suggestive of potential industrial applications.

Continuous Flow Synthesis of Quinolines via a Scalable Tandem Photoisomerization-Cyclization Process

A continuous photochemical process is presented that renders a series of quinoline products via an alkene isomerization and cyclocondensation cascade. It is demonstrated that a high-power LED lamp generates the desired targets with higher productivity and efficiency than a medium-pressure Hg-lamp. The scope of this tandem process is established and allows for the generation of various substituted quinolines in high yields and with throughputs of greater than one gram per hour. Finally, this effective flow process is coupled with a telescoped hydrogenation reaction to render a series of tetrahydroquinolines including the antimalarial natural product galipinine.

Preparation method of trans-disubstituted olefin

The invention relates to the technical field of organic chemical synthesis, and in particular, relates to a preparation method of trans-disubstituted olefin. According to the preparation method, primary alcohol and methyl azacycle are taken as raw materials, transition metal salt, nitric oxide and alkali are taken as catalysts, an organic solution is taken as a reaction medium, and reaction is carried out in an oxygen atmosphere. According to the preparation method, a reaction by-product is only water, the environment is not polluted, the required transition metal catalyst is cheap and easy toobtain, the reaction does not need high temperature, and the reaction cost and the requirements on reaction conditions can be reduced.