77670-15-6

Upstream product

• 24456-60-8 6,7-dimethoxy-1-(methylsulfanyl)-3,4-dihydroisoquinoline 
• 122-59-8 2-phenoxyacetic acid 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 24456-59-5 6,7-dimethoxy-3,4-dihydroisoquinoline-1(2H)-thione 
• 493-49-2 6,7-dimethoxy-3,4-dihydro-2H-isoquinolin-1-one 
• 701-99-5 Phenoxyacetyl chloride 

Downstream Products

• 77670-17-8 7-β-phenoxy-2',3'-dimethoxybenzooctem 

Relevant academic research and scientific papers

A novel entry into 1,2,3,4,5,6-hexahydro-3-benzazocine-4,6-dione and 2-substituted-2,5,6,7-tetrahydro-4-benzazonine-1,3-(4H)-dione

2-substituted-1,2,3,4,5,6-hexahydro-3-benzazocine-4, 6-diones (1a-d) and 2-methoxy-2,5,6,7-tetrahydro-4-benzazonine-1,3-dione 8 were synthesized through an oxidative ring expansion reaction of 6-methylthio-7 substituted-benzo[a] octem (2a-d) and 7-methylt

STEREOSPECIFIC SYNTHESIS OF SOME POLYCYCLIC CIS-β-LACTAMS

Amides 1 on reaction with P2S5 in pyridine give thioamides 2 which on treatment with methyl iodide afford the corresponding 1-methylthio-3,4-dihydroisoquinolines 3.Annelation of these imines with phenoxyacetyl chloride in the presence of triethylamine furnish 6-methylthio-7-phenoxy-2',3'-dimethoxybenzooctem 4a and 6-methylthio-7-phenoxy-2',3'-methylenedioxybenzooctem 4b respectively.Desulphurisation of these β-methylthio-β-lactams with Raney nickel yield the novel polycylic cis-β-lactams 5a and 5b.