77744-52-6Relevant articles and documents
Isolation and biomimetic total synthesis of tomentodiones A-B, terpenoid-conjugated phloroglucinols from the leaves of: Rhodomyrtus tomentosa
Liu, Hong-Xin,Chen, Kai,Tang, Gui-Hua,Yuan, Yun-Fei,Tan, Hai-Bo,Qiu, Sheng-Xiang
, p. 48231 - 48236 (2016)
Tomentodiones A (1) and B (2), a pair of C-11′ epimers of caryophyllene-conjugated phloroglucinols with an unprecedented skeleton, were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated through the application of extensiv
Total syntheses of ericifolione and its analoguesviaa biomimetic inverse-electron-demand Diels-Alder reaction
Chen, Huiyu,Huo, Luqiong,Li, Changgeng,Tan, Haibo,Wang, Sasa,Zheng, Anquan,Zhou, Tingting
supporting information, p. 270 - 273 (2022/01/03)
Driven by bioinspiration and appreciation of the structure of ericifolione, a biomimetic tautomerization/intermolecular inverse-electron-demand hetero Diels-Alder reaction cascade sequence promoted by sodium acetate to rapidly construct sterically hindere
Application of myrtle ketone compound in preparation of novel coronavirus SARS-CoV-2 medicine
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Paragraph 0045; 0048; 0053-0054, (2021/12/07)
The invention discloses application of myrtle ketone compounds in preparation of novel coronavirus SARS-CoV-2 medicaments. The myrtle ketone compound has obvious inhibition effect on novel coronavirus SARS-CoV-2. Mechanisms include, but are not limited to, inhibition of new coronavirus SARS-CoV-2 into cells, preventing the replication of new coronavirus SARS-CoV-2 in the host cell, and timely modulating apoptosis of infected cells. To the myrtle ketone compound provided by the invention, the novel coronavirus SARS-CoV-2 has a remarkable inhibiting effect, and the cytotoxicity is relatively small. It can therefore be used for the prophylaxis or treatment of neoplastic pneumonitis. The invention is expected to provide new candidate drug molecules for clinic treatment of nebrodensis.
The Biomimetic Total Syntheses of the Antiplasmodial Tomentosones A and B
Dong, Chunmao,Hu, Yingjie,Huo, Luqiong,Liu, Hongxin,Tan, Haibo,Wu, Guiyun,Yuan, Yunfei,Zhang, Xiao
supporting information, p. 8007 - 8011 (2020/11/02)
The first biomimetic total syntheses of natural phloroglucinols tomentosones A and B and their analogues have been accomplished. The synthetic strategy primarily referred to the potential biosynthetic precursors and their possible sequence of segments ass