7778-85-0

Usage

Uses

1,2-Dimethoxypropane has been used in the preparation of 1,4-dioxanes.

InChI:InChI=1/C5H12O2/c1-5(7-3)4-6-2/h5H,4H2,1-3H3

Upstream product

• 124-41-4 sodium methylate 
• 107-92-6 butyric acid 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 75-56-9 methyloxirane 
• 57-55-6 propylene glycol 
• 616-38-6 carbonic acid dimethyl ester 

Downstream Products

• 27798-73-8 methyl 3-(3,4-dimethoxyphenyl)propionate 
• 869108-35-0 methyl 3-fluoropyridine-2-carboxylate 
• 74-87-3 methylene chloride 
• 26198-63-0 1,2-Dichloropropane 
• 107-98-2 1-methoxy-2-propanol 
• 1589-47-5 2-methoxypropanol 
• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 32233-43-5 2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanol 

Relevant academic research and scientific papers

On the origin of nitrogen-containing promoters in the cobalt-catalyzed methoxycarbonylation of epoxides

The detailed promotion mechanism of nitrogenous compounds in the cobalt-catalyzed methoxycarbonylation of epoxides has not been studied to date. Herein, we present the intrinsic correlation between nitrogenous promoters and activity and selectivity in the alkoxycarbonylation of epoxides by a comprehensive in situ IR spectroscopy and DFT studies. In situ IR spectroscopy confirmed the acid-base neutralization of the nitrogenous promoters and HCo(CO)4, resulting in reduction of the acidity of the catalyst. With the reduced acid-derived activity for formation of ethers as by-products, the selectivity of desired esters was increased. DFT calculations showed that a nitrogenous base could facilitate the methanolysis of cobalt-acyl species with lowered activation energy, which is considered to be the rate-determining step in the catalytic cycle. As a result, the reaction activity towards carbonylation was also improved by nitrogenous promoters. The present studies will provide new insights to the long-term confusing problems in epoxides carbonylation.

CO2-MEDIATED ETHERIFICATION OF BIO-BASED DIOLS

A method of etherifying glycols or other diols by employing renewable reagents is disclosed. In particular, the method involves contacting a diol with an alkylating agent in an alcoholic solvent, catalyzed with a catalyst (carbonic acid) generated in situ (from CO2). The mono- and di-ether products can serve as valued precursors to an array of renewable surfactants, dispersants, and lubricants, among others.

Anodic Oxidation. Part 17. The Formation of Alkyl Methyl Carbonates in the Hofer-Moest Reaction in Methanol

The liquid products from the electrolysis of sodium butanoate in methanol containing methyl sodium carbonate at a graphite anode include propyl and 1-methylethyl methyl carbonates. 1,1-Dimethylethyl methyl carbonate is amongst the liquid products from the electrolysis of sodium 2,2-dimethylpropanoate in methanol at a platinum anode in the presence or absence of methyl sodium carbonate.Typical secondary products derived from propene or 2-methylpropene are also present in the liquid products from each of these electrolyses.