869108-35-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Fluoro-pyridine-2-carboxylic acid methyl ester is used as a key intermediate in the synthesis of pharmaceutical compounds for its potential to contribute to the development of new drugs. Its unique molecular structure allows for the creation of molecules with specific biological activities, enhancing the therapeutic potential of resulting pharmaceuticals.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Fluoro-pyridine-2-carboxylic acid methyl ester serves as a crucial building block for the synthesis of agrochemical products. Its incorporation into these products can lead to the development of novel agrochemicals with improved efficacy and selectivity, contributing to more effective pest and disease control in agriculture.
Safety Considerations:
Given its potential hazardous properties, 3-Fluoro-pyridine-2-carboxylic acid methyl ester should be handled with care in a controlled laboratory environment to ensure the safety of researchers and the integrity of the compound. Proper safety protocols and equipment are essential when working with this chemical to mitigate any risks associated with its use.

InChI:InChI=1/C7H6FNO2/c1-11-7(10)6-5(8)3-2-4-9-6/h2-4H,1H3

Upstream product

• 152126-31-3 3-fluoro(pyridin-2-yl)carboxylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 372-47-4 3-Fluoropyridine 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 
• 7778-85-0 1,2-dimethoxypropane 

Downstream Products

• 1338091-30-7 tert-butyl 3-(3-fluoropyridin-2-yl)-3-oxopropanoate 
• 1338091-06-7 C₁₆H₁₄FN₅O₂ 
• 1338091-14-7 C₁₆H₁₃FN₄O₂ 
• 1338091-07-8 C₁₇H₁₃FN₆O₂ 
• 1338091-35-2 C₁₇H₁₄FN₅O₃ 
• 1338091-10-3 C₁₇H₁₂FN₅O₂ 
• 31181-79-0 (3-fluoropyridin-2-yl)methanol 
• 122307-44-2 2-(bromomethyl)-3-fluoropyridine 

Relevant academic research and scientific papers

The discovery of potent small molecule cyclic urea activators of STING

STING mediates innate immune responses that are triggered by the presence of cytosolic DNA. Activation of STING to boost antigen recognition is a therapeutic modality that is currently being tested in cancer patients using nucleic-acid based macrocyclic STING ligands. We describe here the discovery of 3,4-dihydroquinazolin-2(1H)-one based 6,6-bicyclic heterocyclic agonists of human STING that activate all known human variants of STING with high potency.

COMPOUNDS AND METHOD FOR TREATMENT OF HIV

The invention relates to a compound of Formulae I and/or II: Formula I Formula II and/or a pharmaceutically-acceptable salt, hydrate, solvate, tautomer, optical isomer, E-isomer, Z-isomer, or combination thereof; X is selected from Se, N-OH, NH, NO2

IMIDAZOPYRIDINE COMPOUND

The present invention provides an imidazopyridine compound represented by formula (I), wherein R1 and R2 each independently represent a C1-6 alkyl group et al; R3 and R4 each independently represent a hydrogen atom, a methyl et al; Ar1 is a divalent substituent representing a monocyclic or bicyclic, 3- to 8-membered aromatic or aliphatic heterocyclic group et al; Ar2 represents an aromatic carbocyclic group, or an aromatic heterocyclic group; W represents -(CH2)m et al, and m indicates an integer of from 0 to 10. This compound acts as a melanin concentrating hormone receptor antagonist, and is useful as treating agents for obesity.