869108-35-0

Basic information

• Product Name: 3-FLUORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: Methyl 3-fluoropyridine-2-carboxylate;3-Fluoro-2-Pyridinecarboxylic acid methyl ester;Methyl 3-fluoropicolinate;3-Fluoro-pyridine-2-carboxylic acid methul ester;2-Pyridinecarboxylicacid, 3-fluoro-, Methyl ester;Methyl 3-fluoro-2-pyridinecarboxylate
• CAS NO: 869108-35-0
• Molecular Formula: C7H6FNO2
• Molecular Weight: 155.13
• Mol File: 869108-35-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 228.8 °C at 760 mmHg
• Flash Point: 92.2 °C
• Appearance: /
• Density: 1.243 g/cm³
• Vapor Pressure: 0.0719mmHg at 25°C
• Refractive Index: 1.49
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 3-FLUORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(869108-35-0)
• EPA Substance Registry System: 3-FLUORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(869108-35-0)

Safety Data

• Hazardous Substances Data: 869108-35-0(Hazardous Substances Data)

Usage

General Description

3-Fluoro-pyridine-2-carboxylic acid methyl ester is an organic compound with the chemical formula C7H6FNO2. It is a methyl ester derivative of 3-fluoro-pyridine-2-carboxylic acid, and is commonly used in the pharmaceutical and agrochemical industries as a building block for the synthesis of various biologically active compounds. This chemical has potential applications in the development of new drugs and agrochemical products due to its unique molecular structure and properties. It is important to handle this compound with caution, as it may have hazardous properties and should be used in a controlled laboratory environment.

InChI:InChI=1/C7H6FNO2/c1-11-7(10)6-5(8)3-2-4-9-6/h2-4H,1H3

Upstream product

• 372-47-4 3-Fluoropyridine 
• 77-78-1 dimethyl sulfate 
• 152126-31-3 3-fluoro(pyridin-2-yl)carboxylic acid 
• 67-56-1 methanol 
• 7778-85-0 1,2-dimethoxypropane 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 1338091-30-7 tert-butyl 3-(3-fluoropyridin-2-yl)-3-oxopropanoate 
• 1338091-06-7 C₁₆H₁₄FN₅O₂ 
• 1338091-14-7 C₁₆H₁₃FN₄O₂ 
• 1338091-07-8 C₁₇H₁₃FN₆O₂ 
• 1338091-35-2 C₁₇H₁₄FN₅O₃ 
• 1338091-10-3 C₁₇H₁₂FN₅O₂ 
• 31181-79-0 (3-fluoropyridin-2-yl)methanol 
• 122307-44-2 2-(bromomethyl)-3-fluoropyridine 

Relevant articles and documents

The discovery of potent small molecule cyclic urea activators of STING

STING mediates innate immune responses that are triggered by the presence of cytosolic DNA. Activation of STING to boost antigen recognition is a therapeutic modality that is currently being tested in cancer patients using nucleic-acid based macrocyclic STING ligands. We describe here the discovery of 3,4-dihydroquinazolin-2(1H)-one based 6,6-bicyclic heterocyclic agonists of human STING that activate all known human variants of STING with high potency.

IMIDAZOPYRIDINE COMPOUND

The present invention provides an imidazopyridine compound represented by formula (I), wherein R1 and R2 each independently represent a C1-6 alkyl group et al; R3 and R4 each independently represent a hydrogen atom, a methyl et al; Ar1 is a divalent substituent representing a monocyclic or bicyclic, 3- to 8-membered aromatic or aliphatic heterocyclic group et al; Ar2 represents an aromatic carbocyclic group, or an aromatic heterocyclic group; W represents -(CH2)m et al, and m indicates an integer of from 0 to 10. This compound acts as a melanin concentrating hormone receptor antagonist, and is useful as treating agents for obesity.