77853-46-4Relevant articles and documents
Divergent Nickel-Catalysed Ring-Opening-Functionalisation of Cyclobutanone Oximes with Organozincs
Angelini, Lucrezia,Leonori, Daniele,Malet Sanz, Laia
supporting information, p. 37 - 40 (2019/12/30)
The development of a nickel-catalysed strategy for the remote alkylation, arylation, vinylation and alkynylation of nitriles is presented. The methodology uses electron-poor O-Ar cyclic oximes and organozincs as coupling partners. This redox process proceeds through the generation of an iminyl radical and its following ring-opening reaction.
Nucleophilic Amination of Methoxy Arenes Promoted by a Sodium Hydride/Iodide Composite
Kaga, Atsushi,Hayashi, Hirohito,Hakamata, Hiroyuki,Oi, Miku,Uchiyama, Masanobu,Takita, Ryo,Chiba, Shunsuke
, p. 11807 - 11811 (2017/09/20)
A method for the nucleophilic amination of methoxy arenes was established by using sodium hydride (NaH) in the presence of lithium iodide (LiI). This method offers an efficient route to benzannulated nitrogen heterocycles. Mechanistic studies showed that the reaction proceeds through an unusual concerted nucleophilic aromatic substitution.
Synthesis of 4-Arylbutanenitriles
Sanchez, Ignacio H.,Aguilar, Maria Antonieta
, p. 55 - 56 (2007/10/02)
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