778596-28-4 Usage
General Description
HS-PEG10-tBu refers to a chemical compound that consists of a thiol group (HS) linked to a ten-unit polyethylene glycol (PEG) chain, which is in turn connected to a tert-butyl (tBu) functional group. HS-PEG10-tBu has unique properties that make it useful in various applications, including drug delivery systems and surface modification of nanoparticles. The thiol group allows for easy conjugation to other molecules and surfaces, while the PEG chain provides water solubility and increased circulation time in the body. The tert-butyl group offers protection against oxidation and chemical degradation. Overall, HS-PEG10-tBu is a versatile and valuable chemical for a range of biomedical and materials science applications.
Check Digit Verification of cas no
The CAS Registry Mumber 778596-28-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,8,5,9 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 778596-28:
(8*7)+(7*7)+(6*8)+(5*5)+(4*9)+(3*6)+(2*2)+(1*8)=244
244 % 10 = 4
So 778596-28-4 is a valid CAS Registry Number.
778596-28-4Relevant articles and documents
Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery
Miller, Michael L.,Roller, Elizabeth E.,Zhao, Robert Y.,Leece, Barbara A.,Ab, Olga,Baloglu, Erkan,Goldmacher, Victor S.,Chari, Ravi V. J.
, p. 4802 - 4805 (2004)
To develop effective taxane-antibody immunoconjugates, we have prepared a series of modified taxanes that have both improved toxicity and solubility in aqueous systems as compared to paclitaxel (1a). These taxanes have been modified at either the C-10 or