778596-28-4 Usage
Uses
Used in Drug Delivery Systems:
HS-PEG10-tBu is used as a carrier molecule for drug delivery systems to improve the solubility, stability, and circulation time of therapeutic agents in the body. The thiol group enables easy conjugation to drug molecules, while the PEG chain enhances water solubility and biocompatibility, leading to better pharmacokinetics and therapeutic efficacy.
Used in Surface Modification of Nanoparticles:
HS-PEG10-tBu is used as a surface modifier for nanoparticles to enhance their stability, biocompatibility, and circulation time in biological systems. The thiol group allows for covalent attachment to nanoparticle surfaces, while the PEG chain provides a hydrophilic and non-fouling layer that reduces protein adsorption and immune clearance, resulting in improved performance in drug delivery and imaging applications.
Used in Biomedical Applications:
HS-PEG10-tBu is used as a component in the development of biomaterials and medical devices, such as hydrogels, scaffolds, and coatings. The thiol group facilitates crosslinking and network formation, while the PEG chain imparts biocompatibility, water solubility, and resistance to protein adsorption, making it suitable for tissue engineering, regenerative medicine, and implantable device applications.
Used in Materials Science Applications:
HS-PEG10-tBu is used as a building block in the synthesis of functional polymers and materials with tailored properties. The thiol group allows for controlled polymerization and self-assembly processes, while the PEG chain and tert-butyl group provide tunable solubility, stability, and reactivity, making it useful for the development of stimuli-responsive materials, self-healing polymers, and other advanced materials with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 778596-28-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,8,5,9 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 778596-28:
(8*7)+(7*7)+(6*8)+(5*5)+(4*9)+(3*6)+(2*2)+(1*8)=244
244 % 10 = 4
So 778596-28-4 is a valid CAS Registry Number.
778596-28-4Relevant academic research and scientific papers
Miller, Michael L.,Roller, Elizabeth E.,Zhao, Robert Y.,Leece, Barbara A.,Ab, Olga,Baloglu, Erkan,Goldmacher, Victor S.,Chari, Ravi V. J.
, p. 4802 - 4805 (2004)
To develop effective taxane-antibody immunoconjugates, we have prepared a series of modified taxanes that have both improved toxicity and solubility in aqueous systems as compared to paclitaxel (1a). These taxanes have been modified at either the C-10 or
