778596-26-2 Usage
Description
Hydroxy-PEG10-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 778596-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,8,5,9 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 778596-26:
(8*7)+(7*7)+(6*8)+(5*5)+(4*9)+(3*6)+(2*2)+(1*6)=242
242 % 10 = 2
So 778596-26-2 is a valid CAS Registry Number.
778596-26-2Relevant articles and documents
Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery
Miller, Michael L.,Roller, Elizabeth E.,Zhao, Robert Y.,Leece, Barbara A.,Ab, Olga,Baloglu, Erkan,Goldmacher, Victor S.,Chari, Ravi V. J.
, p. 4802 - 4805 (2007/10/03)
To develop effective taxane-antibody immunoconjugates, we have prepared a series of modified taxanes that have both improved toxicity and solubility in aqueous systems as compared to paclitaxel (1a). These taxanes have been modified at either the C-10 or
