77866-58-1

Basic information

• Product Name: TRANS-4-N-PROPYLCYCLOHEXANOL
• Synonyms: trans-4-Propylcyclohexanol;trans-4-Propylcyclohexanol
• CAS NO: 77866-58-1
• Molecular Formula: C₉H₁₈O
• Molecular Weight: 142.24
• Mol File: 77866-58-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 36.9°C (estimate)
• Boiling Point: 208°C(lit.)
• Appearance: /
• Density: 0.8998
• Refractive Index: 1.4610 to 1.4650
• PKA: 15.32±0.40(Predicted)
• CAS DataBase Reference: TRANS-4-N-PROPYLCYCLOHEXANOL(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-4-N-PROPYLCYCLOHEXANOL(77866-58-1)
• EPA Substance Registry System: TRANS-4-N-PROPYLCYCLOHEXANOL(77866-58-1)

Safety Data

• Hazardous Substances Data: 77866-58-1(Hazardous Substances Data)

Usage

General Description

TRANS-4-N-PROPYLCYCLOHEXANOL is a chemical compound that belongs to the class of cyclohexanols and is structurally characterized by the presence of a trans-4-n-propyl substituent. It is commonly used as a fragrance ingredient in various consumer products such as perfumes, colognes, and personal care products. The compound is also used as a flavoring agent in food and beverages. TRANS-4-N-PROPYLCYCLOHEXANOL is known for its pleasant, floral and fruity odor and is often used to impart a fresh and clean scent to products. Additionally, it has potential applications in the pharmaceutical and agricultural industries, where it may serve various functions in drug synthesis and pest control.

Upstream product

• 140-67-0 Estragole 
• 94-58-6 dihydrosafrole 
• 94-59-7 1-allyl-3,4-methylenedioxybenzene 
• 97-53-0 4-allylguaiacol 
• 2785-87-7 2-methoxy-4-n-propylphenol 
• 97-54-1 2-methoxy-4-propenylphenol 
• 98790-22-8 cis-4-Propylcyclohexanol 
• 104-46-1 anethole 
• 120-58-1 isosafrole 
• 70-70-2 4-hydroxypropiophenone 
• 40649-36-3 4-propyl-cyclohexanone 
• 645-56-7 4-n-Propylphenol 
• 64-17-5 ethanol 
• 52204-65-6 4-n-propylcyclohexanol 

Downstream Products

• 40649-36-3 4-propyl-cyclohexanone 
• 71458-06-5 trans-4-propyl-1-(hydroxymethyl)cyclohexane 
• 88308-27-4 6-n-Butyl-naphthalen-2-carbonsaeure-trans-4-n-propyl-cyclohexylester 
• 88308-32-1 6-n-Octyl-naphthalen-2-carbonsaeure-trans-4-n-propyl-cyclohexylester 
• 91175-02-9 1-bromo-4-n-propylcyclohexane 
• 1678-92-8 propylcyclohexane 
• 103-65-1 phenylpropane 

Relevant articles and documents

NUCLEUS HYDROGENATION METHOD FOR AROMATIC COMPOUND USING ALCOHOL AND WATER

PROBLEM TO BE SOLVED: To provide a method for the nucleus hydrogenation of an aromatic compound without using hydrogen for the improvement of safety and the diversification of a hydrogen source. SOLUTION: Provided is a method for the nucleus hydrogenation

The highly selective equatorial hydride delivery by biocatalysis: Chemoenzymatic synthesis of trans-2-(4-propylcyclohexyl)-1,3-propanediol via cis-4-propylcyclohexanol

4-Propylcyclohexanone 10a (69 g/L) is reduced by the catalysis of Galactomyces geotrichum JCM 6359 using i-PrOH (4.0 equiv) as an auxiliary substrate for recycling externally supplemented NAD+ (0.001 equiv) in 40 mM potassium phosphate buffer (pH 7.5) for 20 h to provide a mixture of cis-4-propylcyclohexanol 3a [cis/trans (99:0.5); 74%] and unconsumed 10a (22%). Practically pure 3a can be isolated in 69% yield after removing the entailed ketone 10a via bisulfite adduct formation. In the meantime, the crude reduction product [3a/10a (74:22)], without further purification, can be elaborated into trans-2-(4-propylcyclohexyl)-1,3-propanediol 1a, a compound deemed versatile in liquid-crystals development, in 30% overall yield from 10a in four steps.